DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Klk4

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001004101.1	Gene:	Klk4 / 408210	RGDID:	1303228	Length:	256	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	68/244 - (27%)
Similarity:	105/244 - (43%)	Gaps:	51/244 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVARLGEYER 103
            |..:.|||.|.....:|.||...|.|..:.|.|.|.|:..:.||:|||| |.:.:.|. ||.:..
  Rat    26 SSISSRIIQGQDCLPHSQPWQAALFSEDNAFFCSGVLVHPQWVLSAAHC-IQDSYTVG-LGLHNL 88

  Fly   104 TRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPI---------- 158
            ..|:|...   ...|.|:   ..:|..|:..:.|||:.:::|::||:..:.||.|
  Rat    89 EGSQEPGS---RMLEAHL---SIQHPNYNDPSFANDLMLIKLNESVMESNTIRRIPVASQCPTPG 147

  Fly   159 --CVVWDHRWRHYLDKIDLLTATGWGKTQMESDSDALQTLDIRRQPPDVCAKFIGQTIAGNQFCA 221
              |:|                 :|||:.:.......||.:::.....:.|..........:.|||
  Rat   148 DTCLV-----------------SGWGRLKNGKLPSLLQCVNLSVASEETCRLLYDPVYHLSMFCA 195

  Fly   222 GNWD--SNLCNGDSGGPLGAVITHKNTQRFV--------QVGIAS-YTN 259
            |...  .:.||||||||   ::.:::.|..|        |.||.| |||
  Rat   196 GGGPDRKDTCNGDSGGP---IVCNRSLQGLVSMGQGECGQPGIPSVYTN 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	67/239 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	66/238 (28%)
Klk4	NP_001004101.1	Tryp_SPc	35..249	CDD:238113	64/235 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910