DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and MP1

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	80/274 - (29%)
Similarity:	118/274 - (43%)	Gaps:	33/274 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFV----CGGSLITDKLVLTAAHCFIA- 90
            |.||    .....|::.|:.......|||..:..|....|    ||||||..:.|||||||..|
  Fly   128 PNCG----ENFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAI 188

  Fly    91 --NQHLV-ARLGEYERTRSEECTGYYCNFRE------EHMVDAGFKHKLYDPNT--HANDIAILR 144
              :..|. .||||::.:.:.:||......|:      ::.|:....|..|..|:  ..||||:||
  Fly   189 PSDWELTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLR 253

  Fly   145 LSKSVVYRDNIRPIC---VVWDHRWRHYLDKIDLLTATGWGKTQMESDSDALQTLDIRRQPPDVC 206
            |...|.|.|.|.|:|   :...|. ..:|.:  .:...|||:|:....|:.....::...|...|
  Fly   254 LRDEVQYSDFILPVCLPTLASQHN-NIFLGR--KVVVAGWGRTETNFTSNIKLKAELDTVPTSEC 315

  Fly   207 -AKFIGQ--TIAGNQFCAGNWDS-NLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQK--- 264
             .::..|  |:...|.|||..:. :.|.|||||||...........:...|:.||....|..
  Fly   316 NQRYATQRRTVTTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGW 380

  Fly   265 ASVFTDVLSHAEFI 278
            ..|:|.|.::..:|
  Fly   381 PGVYTRVEAYLNWI 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	76/259 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	75/258 (29%)
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	76/259 (29%)
		Tryp_SPc	138..397	CDD:238113	76/260 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463537
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940