DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001004020.1	Gene:	Tmprss11b / 365265	RGDID:	1303278	Length:	420	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	77/279 - (27%)
Similarity:	122/279 - (43%)	Gaps:	33/279 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GIILMFQLLHSGCSQFLDPACGIRTQSRTAY-RIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLI 76
            |.:.:.::......:.::..||.|.:....| ||..|.||:....||...|. ......||.|||
  Rat   156 GSLKLTEITKVDAEKIINNRCGRRPRMSATYDRITGGSTAQKGEWPWQASLR-VNGKHHCGASLI 219

  Fly    77 TDKLVLTAAHCFIAN---QHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHAN 138
            .::.:|||||||:..   ::|....|    ||   .|..|.    :|.|:....|:.|....|.:
  Rat   220 GERFLLTAAHCFLRTNNPKNLTVSFG----TR---VTPAYM----QHYVEEVIIHEDYVKGQHHD 273

  Fly   139 DIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGKTQMESDSD-ALQTLDIRRQP 202
            |:||::|::.|.:|:::..:|:   ..........:.:..||||.......|. .||...|:...
  Rat   274 DVAIIKLTEKVSFRNDVHRVCL---PEATQVFPPGEGVVVTGWGSLSYNGKSPLLLQKASIKIID 335

  Fly   203 PDVC--AKFIGQTIAGNQFCAGNWDS--NLCNGDSGGPLGAVITHKNTQR-FVQVGIASYTNRNC 262
            .:.|  .:..|..|.....|||..:.  :.|.|||||||    .|.|::. :..|||.|: ...|
  Rat   336 TNACNSEEAYGGRIMDTMLCAGYMEGYVDACQGDSGGPL----VHPNSRDIWYLVGIVSW-GHEC 395

  Fly   263 ---QKASVFTDVLSHAEFI 278
               .|..|:..|.|:.::|
  Rat   396 GRVNKPGVYMRVTSYRDWI 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	71/245 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	70/244 (29%)
Tmprss11b	NP_001004020.1	SEA	50..144	CDD:279699
		Tryp_SPc	188..414	CDD:214473	71/245 (29%)
		Tryp_SPc	189..417	CDD:238113	71/246 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910