DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and OVCH1

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_024304736.1	Gene:	OVCH1 / 341350	HGNCID:	23080	Length:	1120	Species:	Homo sapiens

Alignment Length:	329	Identity:	90/329 - (27%)
Similarity:	140/329 - (42%)	Gaps:	67/329 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IGVPTFVGIILMFQLLHSGCSQFLDPACGIR----------TQSRTAYRIINGHTAKYNSSPWMV 60
            :|:....|::|   ||..|..:.|...||||          ..||...||.:...:.....||.|
Human     1 MGLLASAGLLL---LLVIGHPRSLGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQV 62

  Fly    61 FLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVARLGEYERTRSEECTGYYCNFREEHM---- 121
            .|.|....| ||||||.:..|:|||||       :..|.|.:.......:|.|..|:::..
Human    63 SLKSDEHHF-CGGSLIQEDRVVTAAHC-------LDSLSEKQLKNITVTSGEYSLFQKDKQEQNI 119

  Fly   122 -VDAGFKHKLYDPNTHAN-DIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKID---LLTATGW 181
             |.....|..|:...:.: |||:|.|...|.:.:.::|||:....      ||::   |..::||
Human   120 PVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSD------DKVEPGILCLSSGW 178

  Fly   182 GKTQMESD-SDALQTLDIRRQPPDVCAKF--------IGQTIAGNQFCAG--NWDSNLCNGDSGG 235
            ||....|: |:.||.:::.......|...        :|:|:    .|||  :|..:.|.|||||
Human   179 GKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTM----LCAGFPDWGMDACQGDSGG 239

  Fly   236 PLGAVITHKNTQRFVQVGIASY----------TNRNCQKAS--VFTDVLSHAEFILR-VWRMYGK 287
            ||   :..:....::..||.|:          ...|..|||  :|:.|....:||.: ::....:
Human   240 PL---VCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNLFTGLDR 301

  Fly   288 GQTL 291
            ||.|
Human   302 GQPL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	72/265 (27%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	71/264 (27%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113	72/256 (28%)
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910