DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and f2

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_005169022.1	Gene:	f2 / 325881	ZFINID:	ZDB-GENE-030131-4606	Length:	635	Species:	Danio rerio

Alignment Length:	274	Identity:	81/274 - (29%)
Similarity:	122/274 - (44%)	Gaps:	50/274 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SRTAYRIINGHTAKYNSSPWMVFLHSTTDM-FVCGGSLITDKLVLTAAHC---------FIANQH 93
            |.|..||:.|..|:..|:||.|.|:..:.. .:||.|||:|:.:||||||         |..|.
Zfish   368 SYTGSRIVGGDEAEVASAPWQVMLYKRSPQELLCGASLISDEWILTAAHCILYPPWNKNFTIND- 431

  Fly    94 LVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHAN-DIAILRLSKSVVYRDNIRP 157
            ::.|||::.||:.|.      ...:...:|....|..|:...:.| |||:|.:.|.||:...|.|
Zfish   432 IIVRLGKHSRTKYER------GIEKIVAIDEIIVHPKYNWKENLNRDIALLHMKKPVVFTSEIHP 490

  Fly   158 IC-----VVWDHRWRHYLDKIDLLTATGWGKTQMESDSD------ALQTLDIRRQPPDVCAKFIG 211
            :|     :..:..:..|..::     ||||..:....|:      .||.:.:......:|.....
Zfish   491 VCLPTKSIAKNLMFAGYKGRV-----TGWGNLRESWTSNPTNLPTVLQQIHLPIVDQSICRNSTS 550

  Fly   212 QTIAGNQFCAGNW--DS---NLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQ---KASVF 268
            ..|..|.||||..  ||   :.|.||||||.  |:...:..|:.|:||.|: ...|.   |...:
Zfish   551 VIITDNMFCAGYQPDDSKRGDACEGDSGGPF--VMKSPSDNRWYQIGIVSW-GEGCDRDGKYGFY 612

  Fly   269 TDVLSHAEFILRVW 282
            |.:     |.:|.|
Zfish   613 THL-----FRMRRW 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	76/263 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	75/262 (29%)
f2	XP_005169022.1	GLA	39..100	CDD:214503
		KR	126..206	CDD:214527
		KR	228..309	CDD:214527
		Thrombin_light	326..373	CDD:286482	2/4 (50%)
		Tryp_SPc	373..621	CDD:214473	78/267 (29%)
		Tryp_SPc	374..625	CDD:238113	78/268 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910