Protein Alignment CG18636 and HPN

DIOPT Version :10

• Sequence 1: NP_995714.2
• Gene: CG18636 / 2768923
• FlyBaseID: FBgn0032551
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 80/279 - (28%)
• Similarity: 119/279 - (42%)
• Gaps: 46/279 - (16%)

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVAR 97
            ||.|  .....||:.|........||.|.|. .....:|||||::...||||||||.....:::|
Human   153 CGRR--KLPVDRIVGGRDTSLGRWPWQVSLR-YDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSR 214

  Fly    98 LGEYERTRSEECTGYYCNFREEHMVDAGFKHKLY--------DPNT--HANDIAILRLSKSVVYR 152
            ...:....::         ...|.:..|.:..:|        |||:  ::||||::.||..:...
Human   215 WRVFAGAVAQ---------ASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT 270

  Fly   153 DNIRPICV------VWDHRWRHYLDKIDLLTATGWGKTQ-MESDSDALQTLDIRRQPPDVC--AK 208
            :.|:|:|:      :.|.:         :.|.||||.|| ....:..||...:.....|||  |.
Human   271 EYIQPVCLPAAGQALVDGK---------ICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGAD 326

  Fly   209 FIGQTIAGNQFCAGNWDSNL--CNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC---QKASVF 268
            |.|..|....||||..:..:  |.||||||.....:...|.|:...||.|: ...|   ||..|:
Human   327 FYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSW-GTGCALAQKPGVY 390

  Fly   269 TDVLSHAEFILRVWRMYGK 287
            |.|....|:|.:..:.:.:
Human   391 TKVSDFREWIFQAIKTHSE 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	75/256 (29%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	3/7 (43%)
		Tryp_SPc	163..400	CDD:238113	75/256 (29%)