DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_796136.2	Gene:	Tmprss11g / 320454	MGIID:	2444058	Length:	417	Species:	Mus musculus

Alignment Length:	258	Identity:	73/258 - (28%)
Similarity:	119/258 - (46%)	Gaps:	24/258 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQH 93
            |:..||...:.....||.:|..|...|.||...| ....:.:||.|||..:.::|:||||...::
Mouse   170 LNSDCGSGMEYPPIARIADGKPADKASWPWQSSL-QVEGIHLCGASLIGSQWLVTSAHCFDNYKN 233

  Fly    94 LVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPI 158
            .......:.||.|...|        ...|::...|:.|..:.|.:|||:::||..|::.:|:..:
Mouse   234 PKLWTVSFGRTLSSPLT--------TRKVESIIVHENYASHKHDDDIAVVKLSSPVLFSENLHRV 290

  Fly   159 CVVWDHRWRHYLDKIDLLTATGWGKTQMESD-SDALQTLDIRRQPPDVC--AKFIGQTIAGNQFC 220
            |:. |..:: .|.|..:. .||||..:.... .::||.::|.....|||  ....|..|:....|
Mouse   291 CLP-DATFQ-VLPKSKVF-VTGWGALKANGPFPNSLQEVEIEIISNDVCNQVNVYGGAISSGMIC 352

  Fly   221 AGNWDSNL--CNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC---QKASVFTDVLSHAEFI 278
            ||.....|  |.|||||||   :...|..::..:||.|: ..:|   .|..::|.|..:.::|
Mouse   353 AGFLTGKLDACEGDSGGPL---VISDNRNKWYLLGIVSW-GIDCGKENKPGIYTRVTHYRDWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	69/241 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	68/240 (28%)
Tmprss11g	NP_796136.2	SEA	48..142	CDD:279699
		Tryp_SPc	185..411	CDD:214473	69/241 (29%)
		Tryp_SPc	186..414	CDD:238113	69/242 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910