DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_795998.2	Gene:	Tmprss11b / 319875	MGIID:	2442893	Length:	416	Species:	Mus musculus

Alignment Length:	285	Identity:	75/285 - (26%)
Similarity:	119/285 - (41%)	Gaps:	45/285 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GIILMFQLLHSGCSQFLDPACGIRTQSRTAY-RIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLI 76
            |.:.:.::......:.::..||.|.:....| ||..|.||.....||...|. ......||.|||
Mouse   152 GSLKLTEISKVDAEKIINNRCGRRPRMSATYDRITGGSTAHKGEWPWQASLR-VNGKHYCGASLI 215

  Fly    77 TDKLVLTAAHCFIAN---QHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHAN 138
            .::.:|||||||...   ::|....|    ||   .|..|.    :|.|.....|:.|....|.:
Mouse   216 GERFLLTAAHCFQGTNNPKNLTVSFG----TR---VTPAYM----QHSVQEIIIHEDYVKGEHHD 269

  Fly   139 DIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDL------LTATGWGKTQMESDSD-ALQTL 196
            |:|:::|::.|.:.:::..:|:.         :...:      :..||||.......|. .||..
Mouse   270 DVAVIKLTEKVSFNNDVHRVCLP---------ESTQIFPPGEGVVVTGWGSFSYNGKSPLLLQKA 325

  Fly   197 DIRRQPPDVC--AKFIGQTIAGNQFCAGNWDSNL--CNGDSGGPLGAVITHKNTQR-FVQVGIAS 256
            .|:....:.|  .:..|..|.....|||..:.::  |.|||||||    .|.|::. :..|||.|
Mouse   326 SIKIIDTNTCNSEEAYGGRIVDTMLCAGYLEGSIDACQGDSGGPL----VHPNSRDIWYLVGIVS 386

  Fly   257 YTNRNC---QKASVFTDVLSHAEFI 278
            : ...|   .|..|:..|.|:..:|
Mouse   387 W-GHECGRVNKPGVYMRVTSYRNWI 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	69/251 (27%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	68/250 (27%)
Tmprss11b	NP_795998.2	SEA	46..140	CDD:279699
		Tryp_SPc	184..410	CDD:214473	69/251 (27%)
		Tryp_SPc	185..413	CDD:238113	69/252 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910