DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001121000.1	Gene:	Tmprss13 / 300682	RGDID:	1310872	Length:	539	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	77/267 - (28%)
Similarity:	113/267 - (42%)	Gaps:	46/267 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVAR 97
            ||:|..:.   ||:.|.....:..||.|.||..| ..:|||:||..:.||||||||..
  Rat   289 CGLRAMTG---RIVGGALTSESKWPWQVSLHFGT-THICGGTLIDAQWVLTAAHCFFV------- 342

  Fly    98 LGEYERTRSEECTGY--YCNFREEHMV-DAGFKHKL-----YDPNTHANDIAILRLSKSVVYRDN 154
                  ||.:...|:  |......|.: :|....::     |.......|||::||||.:....:
  Rat   343 ------TREKILEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALVRLSKPLTLSAH 401

  Fly   155 IRPICVVWDHRWRHYLDKIDLLTATGWGKTQM--ESDSDALQTLDIRRQPPDVCAKFI--GQTIA 215
            |.|.|:.. |.....|:  :....||:|||:.  |..|..|:.:.:.......|..::  ...:.
  Rat   402 IHPACLPL-HGQTFGLN--ETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLT 463

  Fly   216 GNQFCAGNW----DSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC---QKASVFTDVLS 273
            ....|||:.    ||  |.|||||||   :..:| .|:...|:.|: ...|   .|..|:|.|..
  Rat   464 PRMMCAGDLRGGRDS--CQGDSGGPL---VCEQN-NRWYLAGVTSW-GTGCGQKNKPGVYTKVTE 521

  Fly   274 HAEFILR 280
            ...:|.|
  Rat   522 VLPWIYR 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	72/252 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	71/251 (28%)
Tmprss13	NP_001121000.1	WWbp	<1..69	CDD:304964
		SRCR_2	203..292	CDD:292133	2/2 (100%)
		SRCR	216..288	CDD:278931
		Tryp_SPc	297..526	CDD:214473	72/252 (29%)
		Tryp_SPc	298..526	CDD:238113	71/251 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910