DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and F2

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_075213.2	Gene:	F2 / 29251	RGDID:	61996	Length:	617	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	92/302 - (30%)
Similarity:	128/302 - (42%)	Gaps:	77/302 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIR----TQSRT---------AY---RIINGHTAKYNSSPWMVFL-HSTTDMFVCGGSLITDKL 80
            ||:|    .:|.|         :|   ||:.|..|:...:||.|.| ..:....:||.|||:|:.
  Rat   332 CGLRPLFEKKSLTDKTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRW 396

  Fly    81 VLTAAHCFI--------ANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHA 137
            |||||||.:        ....|:.|:|::.|||.|.      |..:..|::..:.|..|  |...
  Rat   397 VLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYER------NVEKISMLEKIYIHPRY--NWRE 453

  Fly   138 N---DIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDK---IDLLTA------TGWGKTQ----- 185
            |   |||:|:|.|.|.:.|.|.|:|:.         ||   ..||.|      ||||..:
  Rat   454 NLDRDIALLKLKKPVPFSDYIHPVCLP---------DKQTVTSLLQAGYKGRVTGWGNLRETWTT 509

  Fly   186 --MESDSDALQTLDIRRQPPDVCAKFIGQTIAGNQFCAG-----NWDSNLCNGDSGGPLGAVITH 243
              .|.....||.:::......||.......|..|.||||     ....:.|.||||||.  |:..
  Rat   510 NINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPF--VMKS 572

  Fly   244 KNTQRFVQVGIASY---TNRNCQKASVFTDVLSHAEFILRVW 282
            ....|:.|:||.|:   .:|| .|...:|.|     |.|:.|
  Rat   573 PYNHRWYQMGIVSWGEGCDRN-GKYGFYTHV-----FRLKRW 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	83/269 (31%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	82/268 (31%)
F2	NP_075213.2	GLA	25..89	CDD:214503
		KR	107..189	CDD:214527
		Kringle	215..292	CDD:278480
		Thrombin_light	312..359	CDD:286482	6/26 (23%)
		Tryp_SPc	359..608	CDD:214473	85/273 (31%)
		Tryp_SPc	360..612	CDD:238113	85/274 (31%)
		High affinity receptor-binding region which is also known as the TP508 peptide	547..569		9/23 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910