DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and F11

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_006253206.1	Gene:	F11 / 290757	RGDID:	1309364	Length:	622	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	85/302 - (28%)
Similarity:	128/302 - (42%)	Gaps:	68/302 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GVPTFVGIILMFQLLH--SGCSQF------LDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLH 63
            |.||        ::||  .|.|.:      :|..|..:.:.    |:..|..:.:...||.|.||
  Rat   354 GSPT--------RILHGRGGISGYTLRLCKMDNVCTTKIRP----RVFGGAASVHGEWPWQVTLH 406

  Fly    64 STTDMFVCGGSLITDKLVLTAAHCFIANQ---HLVARLGEYERTRSEECTGYYCNFREEHMVDAG 125
             ||...:||||:|.::.:|||||||...:   .|....|...::...|.|.:   ||.:.|:
  Rat   407 -TTQGHLCGGSIIGNRWILTAAHCFSGTETPKTLRVYGGIVNQSEINEDTTF---FRVQEMI--- 464

  Fly   126 FKHKLYDPNTHAN---DIAILRLSKSVVYRDNIRPIC--------VVWDHRWRHYLDKIDLLTAT 179
                ::|..|.|.   |||:|:|..::.|.|..||||        ||....|           .|
  Rat   465 ----IHDQYTSAESGFDIALLKLEPAMNYTDFQRPICLPSKGDRNVVHTECW-----------VT 514

  Fly   180 GWGKTQMESD-SDALQTLDIRRQPPDVC-AKFIGQTIAGNQFCAG--NWDSNLCNGDSGGPLGAV 240
            |||.|:...: ...||...:.....:.| .::....|.....|||  ....:.|.|||||||..
  Rat   515 GWGYTKSRDEVQSTLQKAKVPLVSNEECQTRYRKHKITNKVICAGYKEGGKDTCKGDSGGPLSC- 578

  Fly   241 ITHKNTQRFVQVGIASYTNRNC---QKASVFTDVLSHAEFIL 279
               |:...:..|||.|: ...|   ::..|:|:|..:.::||
  Rat   579 ---KHNGVWHLVGITSW-GEGCGQKERPGVYTNVAKYVDWIL 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	74/254 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	73/253 (29%)
F11	XP_006253206.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..374	CDD:128519	7/27 (26%)
		Tryp_SPc	387..615	CDD:214473	74/254 (29%)
		Tryp_SPc	388..615	CDD:238113	73/253 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910