DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and f10

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	245	Identity:	79/245 - (32%)
Similarity:	115/245 - (46%)	Gaps:	26/245 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 RIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVAR--LGEYERTRS 106
            ||:||........||...|.:..:|..|||:::|:..:|:||||.  |:.|..|  :|||:....
Zfish   244 RIVNGVECPPGDCPWQALLINENNMGFCGGTILTEHFILSAAHCM--NESLSIRVVVGEYDTLVP 306

  Fly   107 E--ECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHY 169
            |  |.|         |.||....||.|.|:|:.||||:::|||.:.:...|.|.|:.........
Zfish   307 EGREAT---------HDVDEILIHKNYQPDTYHNDIALIKLSKPIKFTKYIIPACLPEMKFAERV 362

  Fly   170 LDKIDLLTATGWGKTQMES-DSDALQTLDIRRQPPDVCAKFIGQTIAGNQFCAG--NWDSNLCNG 231
            |.:.|....:|:|:.:... .|..||.|.:.......|.:.....|:|..||||  ..:.:.|.|
Zfish   363 LMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAKCIESSNFKISGRMFCAGYDQEEKDACQG 427

  Fly   232 DSGGPLGAVITHKNTQRFVQVGIASYTNRNCQ---KASVFTDVLSHAEFI 278
            |||||  .|...|||. |: .|:.|: ...|.   |..|:|.|..:..:|
Zfish   428 DSGGP--HVTRFKNTW-FI-TGVVSW-GEGCARKGKYGVYTQVSKYIMWI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	78/243 (32%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	77/242 (32%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342
		Tryp_SPc	244..472	CDD:214473	78/243 (32%)
		Tryp_SPc	245..474	CDD:238113	78/244 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910