Protein Alignment CG18636 and KLK5

DIOPT Version :9

• Sequence 1: NP_995714.2
• Gene: CG18636 / 2768923
• FlyBaseID: FBgn0032551
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_001070959.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 71/280 - (25%)
• Similarity: 113/280 - (40%)
• Gaps: 62/280 - (22%)

  Fly    23 SGCSQFLDPACGIRTQS-RTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAH 86
            ||.:|.|....|...:| .::.|||||.....::.||...|....:...||..|:..:.:|||||
Human    44 SGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAH 108

  Fly    87 CFIANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFK---HKLYDPNTHANDIAILRLSKS 148
            |  ..:....|||.|..:..         :.....:..|.|   |..|....|:||:.:::|::.
Human   109 C--RKKVFRVRLGHYSLSPV---------YESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRR 162

  Fly   149 VVYRDNIRPI------------CVVWDHRWRHYLDKIDLLTATGWGKTQMES--DSDALQTLDIR 199
            :....::|||            |:|                 :|||.|:...  ....||.|:|.
Human   163 IRPTKDVRPINVSSHCPSAGTKCLV-----------------SGWGTTKSPQVHFPKVLQCLNIS 210

  Fly   200 RQPPDVCAKFIGQTIAGNQFCAGN---WDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRN 261
            ......|.....:.|....||||:   .||  |.||||||   |:.:.:.|     |:.|:.:..
Human   211 VLSQKRCEDAYPRQIDDTMFCAGDKAGRDS--CQGDSGGP---VVCNGSLQ-----GLVSWGDYP 265

  Fly   262 C---QKASVFTDVLSHAEFI 278
            |   .:..|:|::....::|
Human   266 CARPNRPGVYTNLCKFTKWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	64/256 (25%)
		Tryp_SPc	45..278	CDD:238113	63/255 (25%)
KLK5	NP_001070959.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		7/23 (30%)
		Tryp_SPc	66..285	CDD:214473	64/256 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910