DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and CG30187

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	92/280 - (32%)
Similarity:	136/280 - (48%)	Gaps:	22/280 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHTALIGVPTFVGIILMFQLLHSGCSQFLDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHST 65
            |.|.|..:|     ::.:.|...|.|.|||..|||    ..|.:|..||.|.:.:|.||..:|:.
  Fly     1 MQTRLAWIP-----VIFWFLKDVGASIFLDQICGI----NIALKITGGHNAAFQNSVWMAAVHNR 56

  Fly    66 TDMFVCGGSLITDKLVLTAAHCFIANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKL 130
            |. |:|||:||..:.|||||||.:........||.|.::...:        |::  |.....|..
  Fly    57 TH-FICGGTLIHKRFVLTAAHCIVDQDVQSVSLGAYNKSDPAD--------RKD--VITAVVHSS 110

  Fly   131 YDPN-THANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGKTQMESDSDALQ 194
            :|.. ::.|||.:|:||..|::...|||||:|.:....:::..:....|.|||..:....||.||
  Fly   111 FDVRASYENDIGLLKLSSDVIFNALIRPICIVLNKSMANHMRNMRTFKAFGWGTLRGNKTSDILQ 175

  Fly   195 TLDIRRQPPDVCAKFIGQTIAGNQFCAGNWDSNLCNGDSGGPL-GAVITHKNTQRFVQVGIASYT 258
            |:.:.....:.|...:....:..|.|||....:.|.||||||| ..|.......|.||.||.|..
  Fly   176 TIILNHLDREECYMELSVYPSEKQICAGVPSGDTCGGDSGGPLTNDVFIQGIGNREVQFGIISVG 240

  Fly   259 NRNCQKASVFTDVLSHAEFI 278
            ..:|....|:||::|.|::|
  Fly   241 KTSCDGQGVYTDLMSFADWI 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	77/235 (33%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	77/234 (33%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	77/235 (33%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960