DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and CG30091

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	92/278 - (33%)
Similarity:	141/278 - (50%)	Gaps:	17/278 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IILMFQLLHS--GCSQFLDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLI 76
            ::|...:|.:  |.::.||..||:..|  ...:|:.|..|....:|||..: .|.|.|:||||:|
  Fly     6 VVLFAWMLTAGRGSARLLDEDCGVPMQ--LIPKIVGGVDAGELKNPWMALI-KTNDEFICGGSVI 67

  Fly    77 TDKLVLTAAHCFIANQHLVAR-------LGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPN 134
            |:|.|||||||...::..:.:       ||.|...    .||.:.:..|.:.|:..:.|..:...
  Fly    68 TNKFVLTAAHCMCTDEECIVKYTQLTVTLGVYHLL----ATGEHNHPHEIYNVERVYIHDSFAIQ 128

  Fly   135 THANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGKTQMESDSDALQTLDIR 199
            .:.||||:|||.||:||:..|:|:|::.:.:.:...|.|...||.|||.|.....|:.||.:.|.
  Fly   129 NYRNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNLQMVKIY 193

  Fly   200 RQPPDVCAKFIGQTIAGNQFCAGN-WDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQ 263
            |....:|......|.....||||. ...:.|..||||||...:.....:|..|:||.|....:|:
  Fly   194 RIDRKMCEAAFWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDCR 258

  Fly   264 KASVFTDVLSHAEFILRV 281
            ...::|||:.|.:||.|:
  Fly   259 GFGMYTDVMGHIDFIERI 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	81/241 (34%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	81/240 (34%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	81/241 (34%)
		Tryp_SPc	37..276	CDD:238113	83/243 (34%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463347
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.740