DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Tmprss11f

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_848845.1	Gene:	Tmprss11f / 243083	MGIID:	2442348	Length:	439	Species:	Mus musculus

Alignment Length:	273	Identity:	73/273 - (26%)
Similarity:	117/273 - (42%)	Gaps:	45/273 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LDPACGIRTQ--------SRTAYRIING-HTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTA 84
            |:..||||..        |.:..||:.| .||.....||...|........||.:||::..:|||
Mouse   183 LNSRCGIRMSSSNIPLPASSSTERIVQGRETAMEGEWPWQASLQLIGAGHQCGATLISNTWLLTA 247

  Fly    85 AHCFIANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSV 149
            ||||..|:.....:..:..|.:....        :..|.....|:.|..:|:.||||:.:|:..|
Mouse   248 AHCFWKNRDPTKWIVTFGTTITPPLV--------KRSVGKIIIHEEYHRDTNENDIALAQLTTRV 304

  Fly   150 VYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGK------TQMESDSDALQTLDIRRQPPDVCAK 208
            .:.:.::.:|:. |...:  |.....:..||:|.      ||.:.....::|:.     .|||.:
Mouse   305 EFSNVVQRVCLP-DSSMK--LPPKTSVFVTGFGSIVDDGPTQNKLRQARVETIG-----SDVCNR 361

  Fly   209 ---FIGQTIAGNQFCAGNWDSNL--CNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC---QKA 265
               :.| .|.....|||..:..:  |.|||||||    .:.|...:..|||.|: .::|   .|.
Mouse   362 KDVYDG-LITPGMLCAGFMEGKIDACKGDSGGPL----VYDNRDIWYIVGIVSW-GQSCALPNKP 420

  Fly   266 SVFTDVLSHAEFI 278
            .|:|.|..:.::|
Mouse   421 GVYTRVTKYRDWI 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	66/248 (27%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	65/247 (26%)
Tmprss11f	NP_848845.1	SEA	60..164	CDD:396113
Tmprss11f	NP_848845.1	Tryp_SPc	207..436	CDD:238113	66/249 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910