DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Tmprss7

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_766043.3	Gene:	Tmprss7 / 208171	MGIID:	2686594	Length:	829	Species:	Mus musculus

Alignment Length:	297	Identity:	80/297 - (26%)
Similarity:	123/297 - (41%)	Gaps:	65/297 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LMFQLLHSGCSQFLD-------PACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGG 73
            :.|:..::.|...:|       ..||....|...:||:.|..::..:.||.|.||.....: ||.
Mouse   556 ICFRKQNAQCDGIVDCPDGSDEEGCGCSRSSSFLHRIVGGSDSQEGTWPWQVSLHFVGSAY-CGA 619

  Fly    74 SLITDKLVLTAAHCFIANQ-----HLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDP 133
            |:|:.:.:|:|||||..|:     ...|.||.|.:.          |.:....|.....|:.|:.
Mouse   620 SVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQG----------NAKFISPVRRIVVHEYYNS 674

  Fly   134 NTHANDIAILRLSKS--VVYRDNIRPICV------------VWDHRWRHYLDKIDLLTATGWGKT 184
            .|...|||:|:||.:  ...:..|:|||:            .|               .||||:
Mouse   675 QTFDYDIALLQLSIAWPETLKQLIQPICIPPAGQKVRSGEKCW---------------VTGWGR- 723

  Fly   185 QMESD---SDALQTLDIRRQPPDVCAKFIGQTIAGNQFCAG--NWDSNLCNGDSGGPLGAVITHK 244
            :.|:|   |..||..::......||....| .|.....|||  :..|:.|.|||||||..  ..|
Mouse   724 RHEADSKGSPVLQQAEVELIDQTVCVSTYG-IITSRMLCAGVMSGKSDACKGDSGGPLSC--RRK 785

  Fly   245 NTQRFVQVGIASYTNRNCQKAS---VFTDVLSHAEFI 278
            :..:::..||.|: ...|.:.:   |:|.|.|...:|
Mouse   786 SDGKWILTGIVSW-GHGCGRPNFPGVYTRVSSFVPWI 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	73/260 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	72/259 (28%)
Tmprss7	NP_766043.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..52
		SEA	94..194	CDD:366610
		CUB	<257..345	CDD:238001
		LDLa	470..504	CDD:238060
		LDLa	545..580	CDD:238060	3/23 (13%)
		Tryp_SPc	591..821	CDD:214473	73/260 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000