DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Tmprss11a

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_006534903.1	Gene:	Tmprss11a / 194597	MGIID:	2684853	Length:	392	Species:	Mus musculus

Alignment Length:	282	Identity:	78/282 - (27%)
Similarity:	116/282 - (41%)	Gaps:	80/282 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVAR 97
            ||.|.....|.||::|:.|...:.||.|.| ..:::..|||:||.:..|:||||||
Mouse   149 CGKRAIPLIANRIVSGNPAAKGAWPWQVSL-QRSNIHQCGGTLIGNMWVVTAAHCF--------- 203

  Fly    98 LGEYERTRSEECTGYYCNFRE--------------EHMVDAGFKHKLYDPNTHANDIAILRLSKS 148
                 ||.|        |.|:              :..|.....|:.|.|....:|||:::.|..
Mouse   204 -----RTNS--------NPRQWTLSFGTTINPPLMKRDVRRIIMHERYRPPARDHDIALVQFSPR 255

  Fly   149 VVYRDNIRPICV------------VWDHRWRHYLDKIDLLTATGWGKTQMESDS-DALQTLDIRR 200
            |.:.|.:|.||:            |:               .||:|......:| :.|:...::.
Mouse   256 VTFSDEVRRICLPEPSASFPPNSTVY---------------ITGFGALYYGGESQNELREARVQI 305

  Fly   201 QPPDVCAK--FIGQTIAGNQFCA----GNWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTN 259
            ...|:|.|  ..|..|....|||    ||:|:  |.|||||||   :...|...:..:||.|:.:
Mouse   306 ISNDICKKRHVYGNEIKRGMFCAGFLEGNYDA--CRGDSGGPL---VIRDNKDTWYLIGIVSWGD 365

  Fly   260 RNC---QKASVFTDVLSHAEFI 278
             ||   .|..|:|.|..:..:|
Mouse   366 -NCGQKNKPGVYTQVTYYRHWI 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	73/269 (27%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	72/268 (27%)
Tmprss11a	XP_006534903.1	SEA	42..135	CDD:366610
Tmprss11a	XP_006534903.1	Tryp_SPc	161..389	CDD:238113	73/270 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910