DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Plau

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_032899.1	Gene:	Plau / 18792	MGIID:	97611	Length:	433	Species:	Mus musculus

Alignment Length:	308	Identity:	81/308 - (26%)
Similarity:	126/308 - (40%)	Gaps:	68/308 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IGVPTFVGIILMFQLLHSGCSQFLDPACGIRTQS--------RTAYRIINGHTAKYNSSPWMVFL 62
            ||:..||.     :.:...||....|:..:..|.        |..::|:.|...:..:.||...:
Mouse   138 IGLRQFVQ-----ECMVHDCSLSKKPSSSVDQQGFQCGQKALRPRFKIVGGEFTEVENQPWFAAI 197

  Fly    63 H-----STTDMFVCGGSLITDKLVLTAAHCFI---ANQHLVARLGEYERTRSEECTGYYCNFREE 119
            :     .:...|.||||||:...|.:||||||   ..::.|..||:   ::..........|..|
Mouse   198 YQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQ---SKESSYNPGEMKFEVE 259

  Fly   120 HMVDAGFKHKLY--DPNTHANDIAILRLSKSVVY----RDNIRPICVVWDHRWRHYLDKIDLLTA 178
            .::    .|:.|  |...:.||||:|::..|...    ..:|:.||:........:....::
Mouse   260 QLI----LHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQTICLPPRFTDAPFGSDCEI--- 317

  Fly   179 TGWGKTQMESDSDALQTLDIR------------RQPPDVCAKFIGQTIAGNQFCAGN--WDSNLC 229
            ||:||   ||:||.|...:::            .||     .:.|..|.....||.:  |.::.|
Mouse   318 TGFGK---ESESDYLYPKNLKMSVVKLVSHEQCMQP-----HYYGSEINYKMLCAADPEWKTDSC 374

  Fly   230 NGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC---QKASVFTDVLSH 274
            .|||||||...|..:.|..    ||.|: .|.|   .|..|:|.| ||
Mouse   375 KGDSGGPLICNIEGRPTLS----GIVSW-GRGCAEKNKPGVYTRV-SH 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	72/262 (27%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	72/261 (28%)
Plau	NP_032899.1	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	35..58
		Kringle	71..152	CDD:333799	4/18 (22%)
		Connecting peptide	153..179		4/25 (16%)
		Tryp_SPc	180..424	CDD:238113	72/261 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910