DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Plat

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_032898.2	Gene:	Plat / 18791	MGIID:	97610	Length:	559	Species:	Mus musculus

Alignment Length:	290	Identity:	83/290 - (28%)
Similarity:	121/290 - (41%)	Gaps:	62/290 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 SGCSQFLDPACGIRTQSRTAYRIINGHTAKYNSSPWM--VFL---HSTTDMFVCGGSLITDKLVL 82
            |.||     .||:|...|..:||..|......|.||.  :|:   .|..:.|:|||.||:...||
Mouse   292 SPCS-----TCGLRQYKRPQFRIKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVL 351

  Fly    83 TAAHCFIAN---QHLVARLGE-YERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAIL 143
            :|||||:..   .||...||. |.....||        .:...::....|:.:|.:|:.||||:|
Mouse   352 SAAHCFLERFPPNHLKVVLGRTYRVVPGEE--------EQTFEIEKYIVHEEFDDDTYDNDIALL 408

  Fly   144 RL---SKSVVYR-DNIRPICVV--------WDHRWRHYLDKIDLLTATGWGKTQMESD--SDALQ 194
            :|   ||..... .::...|:.        |..           ...:|:||.:..|.  ||.|:
Mouse   409 QLRSQSKQCAQESSSVGTACLPDPNLQLPDWTE-----------CELSGYGKHEASSPFFSDRLK 462

  Fly   195 TLDIRRQPPDVCAK--FIGQTIAGNQFCAGNWDS-------NLCNGDSGGPLGAVITHKNTQRFV 250
            ...:|..|...|..  ...:|:..|..|||:..|       :.|.|||||||..:|..:.|
Mouse   463 EAHVRLYPSSRCTSQHLFNKTVTNNMLCAGDTRSGGNQDLHDACQGDSGGPLVCMINKQMT---- 523

  Fly   251 QVGIASYTNRNCQK--ASVFTDVLSHAEFI 278
            ..||.|:.....||  ..|:|.|.::.::|
Mouse   524 LTGIISWGLGCGQKDVPGVYTKVTNYLDWI 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	75/267 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	74/266 (28%)
Plat	NP_032898.2	FN1	38..80	CDD:214494
		Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		EGF	83..115	CDD:394967
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056	1/2 (50%)
		Tryp_SPc	311..556	CDD:238113	74/266 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910