DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and try-5

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_505421.3	Gene:	try-5 / 187088	WormBaseID:	WBGene00006623	Length:	327	Species:	Caenorhabditis elegans

Alignment Length:	331	Identity:	82/331 - (24%)
Similarity:	134/331 - (40%)	Gaps:	80/331 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IILMFQLL----HSGCSQFLDPACGIRTQSRTAYRIIN--GHTAK-YNSSPWMVFLHSTTDM--- 68
            |:.:||:|    .:....:.|..|| |..:.|::.:.:  |:|.. .:.:||.|.:......
Worm     6 IVFLFQVLVVIKGTKLKYYNDELCG-RQSTYTSFMLTDAAGNTGNPTHLAPWAVQIRVKARKGDF 69

  Fly    69 -FVCGGSLITDKLVLTAAHCFIANQHLVARLGEYERTRSEECTGYYCNFREEH---------MVD 123
             .:|||:|||.|.||||||||  .:|..|:   .|.......:|.||...:..         :|.
Worm    70 EVICGGTLITLKHVLTAAHCF--QKHFGAK---KEGGEENSMSGRYCESNQRFTDSEILTRTVVT 129

  Fly   124 AG-----FKHKLYDPN--------------------TH---ANDIAILRLSKSVVYRDNIRPICV 160
            .|     .:.|....|                    ||   .|||.||.|..::...:.....|:
Worm   130 VGAMCTRLEQKYGCVNEKQNGKTLKISRFAIGDFYKTHCEQGNDIVILELESTIDDVEGANYACL 194

  Fly   161 VWDHRWRHYLDKIDL-----LTATGWGKTQMESDSDA----LQTLDIRRQPPDVCAKFIGQTIAG 216
                   .:|.::::     :|:.|||....:...:|    :|.|.:..:....|.:..|.:|..
Worm   195 -------PFLPEVNIQSGANVTSFGWGSDPGKGFDNAAFPMIQVLTLATETLATCEENWGTSIPF 252

  Fly   217 NQFC-AGNWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQ-------KASVFTDVLS 273
            :.|| |...|.|:|:|||||  |......::.|...:.|.||.:...|       ::.:.|||..
Worm   253 DSFCTAEEEDKNVCSGDSGG--GLTFHQSDSAREFIIAIVSYGSDCVQLIGGSEPRSQINTDVRK 315

  Fly   274 HAEFIL 279
            |.:||:
Worm   316 HQKFIV 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	71/294 (24%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	71/293 (24%)
try-5	NP_505421.3	Tryp_SPc	48..296	CDD:389826	64/261 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010