DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Masp2

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001003893.1	Gene:	Masp2 / 17175	MGIID:	1330832	Length:	685	Species:	Mus musculus

Alignment Length:	265	Identity:	82/265 - (30%)
Similarity:	116/265 - (43%)	Gaps:	32/265 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCF----IA 90
            :|.||:.|.: ...||:.|..||....||.|.|...|.  ...|:||.|..||||||..    :|
Mouse   430 EPVCGLSTHT-IGGRIVGGQPAKPGDFPWQVLLLGQTT--AAAGALIHDNWVLTAAHAVYEKRMA 491

  Fly    91 NQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKL-YDPNTHANDIAILRLSKSVVYRDN 154
            ...|..|:|..:|....    |...:.||..:..|:.|.. :|     ||||:::|...|....:
Mouse   492 ASSLNIRMGILKRLSPH----YTQAWPEEIFIHEGYTHGAGFD-----NDIALIKLKNKVTINGS 547

  Fly   155 IRPICVVWDHRWRHYLDKIDLL-TATGWGKTQMESDSDALQTLDIRRQPPDVCAK-----FIGQT 213
            |.|:|:  ..:....|.:.|.. |..|||.||....:..|..:||.......|..     :.|..
Mouse   548 IMPVCL--PRKEAASLMRTDFTGTVAGWGLTQKGLLARNLMFVDIPIADHQKCTAVYEKLYPGVR 610

  Fly   214 IAGNQFCAG--NWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQKA---SVFTDVLS 273
            ::.|..|||  ....:.|.|||||.|  |.....|||:...||.|:.:.||..|   .|:|.|::
Mouse   611 VSANMLCAGLETGGKDSCRGDSGGAL--VFLDNETQRWFVGGIVSWGSINCGAADQYGVYTKVIN 673

  Fly   274 HAEFI 278
            :..:|
Mouse   674 YIPWI 678

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	77/249 (31%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	76/248 (31%)
Masp2	NP_001003893.1	CUB	19..136	CDD:238001
		FXa_inhibition	152..180	CDD:291342
		CUB	184..293	CDD:278839
		Sushi	300..361	CDD:278512
		Sushi	366..429	CDD:278512
		Tryp_SPc	443..678	CDD:214473	77/249 (31%)
		Tryp_SPc	444..681	CDD:238113	77/250 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910