DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP011719

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_320793.4	Gene:	AgaP_AGAP011719 / 1280920	VectorBaseID:	AGAP011719	Length:	762	Species:	Anopheles gambiae

Alignment Length:	244	Identity:	68/244 - (27%)
Similarity:	116/244 - (47%)	Gaps:	34/244 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 TDMFVCGGSLITDKLVLTAAHCFIANQHL----VARLGEYERTRSEECTGYYCNFREEHMVDAGF 126
            |..:.||||||.:..:||||||:.....:    |.|:|:.....:::     ..|.:|..:....
Mosquito    44 TVQWKCGGSLIWENYILTAAHCYADPDTILSPDVIRIGDLNLFDADD-----DEFVQERKIVQII 103

  Fly   127 KHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKI--DLLTATGWGKTQM-ES 188
            :|.|::.:|...|:|:|:|.|.|:..:.:.|.|:..|       |.|  ..|...|||:|.. :.
Mosquito   104 RHPLHNASTVYYDLALLKLDKKVIQSEGVIPTCLWLD-------DSIPFSTLEVAGWGQTGFGKE 161

  Fly   189 DSDALQTLDIRRQPPDVCAKF--------IGQTIAGNQFCAGNWDS--NLCNGDSGGPLGAVITH 243
            .|:.|...:::......|||:        :|..:|.:|.||  ||.  :.|.|||||||...:.:
Mosquito   162 KSNMLLKAELKLMTNTECAKYNNKRTQRRLGNDLADHQLCA--WDEVMDTCPGDSGGPLHYNLYY 224

  Fly   244 KNTQRFVQVGIASYTNRNC--QKASVFTDVLSHAEFILRVWRMYGKGQT 290
            |:|:....||:.|: .:.|  .:..|:..|....::|:...:..|:..|
Mosquito   225 KHTKIPFLVGVTSF-GKACAVSQPGVYVKVAKFKQWIIETLQEQGEQVT 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	65/230 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	65/230 (28%)
AgaP_AGAP011719	XP_320793.4	Tryp_SPc	19..263	CDD:238113	66/233 (28%)
		Tryp_SPc	19..260	CDD:214473	65/230 (28%)
		Tryp_SPc	318..537	CDD:304450
		Tryp_SPc	653..>762	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910