DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP011908

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_320621.4	Gene:	AgaP_AGAP011908 / 1280755	VectorBaseID:	AGAP011908	Length:	391	Species:	Anopheles gambiae

Alignment Length:	269	Identity:	79/269 - (29%)
Similarity:	124/269 - (46%)	Gaps:	39/269 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 CSQFLDPA---CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHS--TTDMFVCGGSLITDKLVLTA 84
            |...:.|.   ||   .|||| :|:.|..|..|....||.|..  |.::| |.|::|:.:.||||
Mosquito   135 CRLVVQPQECDCG---WSRTA-KIVGGSVAGVNEYTAMVGLLDPLTVNVF-CSGAIISSRYVLTA 194

  Fly    85 AHC---FIANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLS 146
            |||   ..:...:.|.:|::: .||...|.|...:..|.::    .|:.|:..|..||||:|:.|
Mosquito   195 AHCARTIPSVSRVQALVGDHD-YRSGLDTPYSAIYNIEQII----SHEYYNEQTRNNDIALLKTS 254

  Fly   147 KSVVYRDNIRPICVVWDHRWRHYLD-KIDLLTATGWGKTQMESDSDAL---QTLDIRRQPPDVCA 207
            ..:.:...:.|||:.:.:....:.. .:|:   .|||.|........:   .||:: .|..:..|
Mosquito   255 TEMDFNRGVGPICLPFTYSTYSFGGLSVDI---AGWGTTSFGGPMSTILRKTTLNV-LQNANCTA 315

  Fly   208 KFIG-QTIAGNQFCAGNWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQKA--SVFT 269
            .::. |.|.  .|..|. ||  |..||||.|..    :.:||...:||.||.:. |..:  ||.|
Mosquito   316 PYVNDQKIC--TFAVGR-DS--CQYDSGGALFL----RGSQRMYSIGIISYGSA-CAASTPSVAT 370

  Fly   270 DVLSHAEFI 278
            .|.::..:|
Mosquito   371 RVTAYLSWI 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	70/245 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	70/244 (29%)
AgaP_AGAP011908	XP_320621.4	CUB	26..>106	CDD:294042
		Tryp_SPc	153..379	CDD:214473	70/245 (29%)
		Tryp_SPc	154..382	CDD:238113	71/246 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910