DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP012022

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_320504.4	Gene:	AgaP_AGAP012022 / 1280645	VectorBaseID:	AGAP012022	Length:	737	Species:	Anopheles gambiae

Alignment Length:	277	Identity:	73/277 - (26%)
Similarity:	123/277 - (44%)	Gaps:	42/277 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PACGIRTQSRT-AYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHL 94
            ||.|.....|. |:....|.|.:..|..|:           ||||||.:..:||||||...:.::
Mosquito    20 PAAGSPAYLREFAHIAAIGWTNEDQSVRWL-----------CGGSLIWENFILTAAHCAADDNNV 73

  Fly    95 ---VARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIR 156
               |||:|:......|:     ..|.::..:....:|..:..|::..|||:::|.::|...:.:.
Mosquito    74 PPDVARMGDINIYSDED-----DEFAQQLKIVEIIRHPKHKYNSNYYDIALMKLERNVTLHNTVA 133

  Fly   157 PICVVWDHRWRHYLDKIDL--LTATGWGKTQMESDSDALQTLDIRRQP--PDVCA-------KFI 210
            |.|:..|       |:|..  |.|.|||:|....|: ....|.::..|  .|.|:       :.:
Mosquito   134 PTCLWLD-------DEIRFPELLAAGWGRTGFGEDT-TKTLLKVQLAPITNDKCSTHYQRGVRKL 190

  Fly   211 GQTIAGNQFCAGNWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC--QKASVFTDVLS 273
            ...:..:|||||:...:.|.|||||||...:..|.......||:.|: .:.|  ....|:..|..
Mosquito   191 ENGLMDHQFCAGDEKMDTCPGDSGGPLHVKLFKKWKLVPFLVGVTSF-GKACGISAPGVYVKVSK 254

  Fly   274 HAEFILRVWRMYGKGQT 290
            .:::|:...:.:|:..|
Mosquito   255 FSDWIIETLQRHGEMAT 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	65/249 (26%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	65/248 (26%)
AgaP_AGAP012022	XP_320504.4	Tryp_SPc	23..262	CDD:238113	69/263 (26%)
		Tryp_SPc	23..259	CDD:214473	68/260 (26%)
		Tryp_SPc	335..533	CDD:304450
		Tryp_SPc	648..>729	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910