DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP012328

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_320219.3	Gene:	AgaP_AGAP012328 / 1280372	VectorBaseID:	AGAP012328	Length:	324	Species:	Anopheles gambiae

Alignment Length:	284	Identity:	86/284 - (30%)
Similarity:	129/284 - (45%)	Gaps:	53/284 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DPACGIRTQSRTAYRIINGHTAKYNSSPWMVFL-----HSTTDMFVCGGSLITDKLVLTAAHCFI 89
            |..||::..:    ||:.|.....:..|||..|     ...|..|.|||:|:..|.||:|||||:
Mosquito    52 DEVCGVQMDN----RIVGGQRTSIDQYPWMALLQYINHRKGTKRFACGGALLNRKFVLSAAHCFV 112

  Fly    90 -----ANQHLVARLGEYERTRSE----------ECTGYYCNFREEHMVDAGFKHKLYDPNTHA-- 137
                 ...|.| ||||:: |.||          .|.....:...|.::    .|:.|..| ||
Mosquito   113 RLPAGVELHKV-RLGEWD-TDSEIDCEDLDDELSCASPVQDLDYERII----IHEGYTGN-HADR 170

  Fly   138 -NDIAILRLSKSVVYRDNIRPICVV---WDHRWRHYLDKIDLLTATGWGKTQMESDSD-----AL 193
             ||||::.||.|..|.|.::|||:.   ..::.:.|...   :.|.|||:|:..|.|.     .|
Mosquito   171 ENDIALIELSGSAKYNDFVKPICLPEPGTPNKEKLYFGS---MWAAGWGRTETASGSRFKLYVPL 232

  Fly   194 QTLDIRRQPPDVCAKFIGQTIAGNQFCA-GNWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASY 257
            ...|: :...:...:.:...:...|||| |....:.|||||||||   :....|..:| ||:.|:
Mosquito   233 DLFDL-QSCNETYQRRVKVPLTETQFCAMGTPGKDTCNGDSGGPL---MKTMKTLHYV-VGVVSF 292

  Fly   258 TNRNCQKA--SVFTDVLSHAEFIL 279
            ..:.|...  :|:|.|....::|:
Mosquito   293 GPQRCGSGIPAVYTRVDKFYDWIV 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	82/267 (31%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	81/266 (30%)
AgaP_AGAP012328	XP_320219.3	CLIP	1..45	CDD:295450
		Tryp_SPc	62..315	CDD:214473	82/267 (31%)
		Tryp_SPc	63..315	CDD:238113	81/266 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910