DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP008911

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_319658.4	Gene:	AgaP_AGAP008911 / 1279878	VectorBaseID:	AGAP008911	Length:	579	Species:	Anopheles gambiae

Alignment Length:	320	Identity:	73/320 - (22%)
Similarity:	126/320 - (39%)	Gaps:	75/320 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLHSGC------------SQFLDPACG---IRTQSRTAYRIINGHTAKYNSSPWMVFLH---STT 66
            ||..||            .|.|   ||   ::|.|..     |...|.....||...::   ...
Mosquito     9 LLLMGCLYLVTQIRGQDEDQLL---CGRRKVQTNSMN-----NNGDAIAGHWPWYAAIYHRKGEK 65

  Fly    67 DMFVCGGSLITDKLVLTAAHC------FIANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAG 125
            ..:.||||::.:..:|||::|      .|:...:...:|:....::......| :.| |.:|..|
Mosquito    66 QEYACGGSILDETTILTASNCVYTPSGVISAALVTVHVGQIHPKQASAYAQMY-DVR-EIVVHPG 128

  Fly   126 FKHKLYDPNTHANDIAILRLSKSV-VYRDNIRPICVVWDHRWRHYLDK-IDLL-----TATGWGK 183
            |...     :..||||:::|:.|: :..:.::|:|:     |.  :|. ::|:     |..|:|.
Mosquito   129 FSEA-----STINDIALIKLTASITLTTEYVQPVCL-----WT--MDSALELIVGRNGTVVGFGP 181

  Fly   184 TQMES--DSDALQTLDIRRQPPDVC----AKFIGQTIAGNQFCAGNWD--SNLCNGDSGGPLGAV 240
            .:...  ..:.||...|....|..|    ....|..:....||.....  :..||||||..|
Mosquito   182 NERRDVVSGEQLQQATIGVVDPQTCIASDPAIFGTHLPVETFCGKGLQNGAGACNGDSGDGL--- 243

  Fly   241 ITHKNTQRFVQVGIASY-----TNRNCQ--KASVFTDVLSHAEFILRVWRMYGKGQTLPI 293
            ....:.|.||:..:|..     ::..|.  :.:|:|||..:.::|.|    |...:.||:
Mosquito   244 FFEVSGQWFVRGLVARLQPVRESDGLCDPLQYTVYTDVAKYVDWIKR----YVDPRVLPV 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	58/264 (22%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	58/263 (22%)
AgaP_AGAP008911	XP_319658.4	Tryp_SPc	359..573	CDD:304450
		Tryp_SPc	46..290	CDD:238113	58/260 (22%)
		Tryp_SPc	46..288	CDD:214473	57/258 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910