DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and SCRASP2

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_316661.5	Gene:	SCRASP2 / 1277217	VectorBaseID:	AGAP006631	Length:	1343	Species:	Anopheles gambiae

Alignment Length:	282	Identity:	76/282 - (26%)
Similarity:	127/282 - (45%)	Gaps:	41/282 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 CSQFLDPACG-IRTQS--RTAYRIINGHTAKYNSSPWM-VFLHSTTDMFVCGGSLITDKLVLTAA 85
            ||.|   .|| :|.:.  :...||:.|.|:.....|:: ..|....::|.|.|.||.|:.||||:
Mosquito  1060 CSNF---ECGKVRNRKYFKATKRIVGGSTSNPGDWPFIAAILGGPEEVFYCAGVLIADQWVLTAS 1121

  Fly    86 HCFIAN---QHLVARLGEY------ERTRSEECTGYYCNFREEHMVDAGFKHKLYDPN-THANDI 140
            || |.|   .|.:..:.::      .|.||..   ||   .::..|.....|.:|:.: .|.|||
Mosquito  1122 HC-IGNSPTSHTMRNVNDWTIQLGITRRRSHT---YY---GQKVKVKTVIPHPMYNLHIPHDNDI 1179

  Fly   141 AILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGKTQMESDS-------DALQTLDI 198
            |:.:|:..|.:.:::.|:|:...| .|.....|: .|..||||.:..:.:       ..|..:::
Mosquito  1180 ALFQLATRVAFHEHLLPVCLPPPH-IRELPTGIN-CTVVGWGKREERNSTPNGASYEPTLNEVNV 1242

  Fly   199 RRQPPDVCAKFIGQ-TIAGNQFCAGNWDS--NLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNR 260
            .....::|..::.. .:.....|||..:.  :.|.|||||||.....::..:.||. ||.|:..|
Mosquito  1243 PIVSRELCIDWLETFNVTEGMICAGYQEGGRDACQGDSGGPLLCPYPNEKDRWFVG-GIVSWGVR 1306

  Fly   261 NC---QKASVFTDVLSHAEFIL 279
             |   :...|:.:|.....:||
Mosquito  1307 -CAHPKLPGVYANVPKFIPWIL 1327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	68/257 (26%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	67/256 (26%)
SCRASP2	XP_316661.5	Fz	753..857	CDD:279700
		LDLa	889..918	CDD:238060
		LDLa	921..955	CDD:294076
		SRCR_2	956..>1011	CDD:295335
		Tryp_SPc	1079..1326	CDD:214473	68/257 (26%)
		Tryp_SPc	1080..1326	CDD:238113	67/256 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910