DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and CLIPB8

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_312743.1	Gene:	CLIPB8 / 1273740	VectorBaseID:	AGAP003057	Length:	405	Species:	Anopheles gambiae

Alignment Length:	289	Identity:	80/289 - (27%)
Similarity:	127/289 - (43%)	Gaps:	48/289 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFV----CGGSLITDKLVLTAAHCFIANQ 92
            :|||  ||..| :|..|..|:.:..|||..|....|...    |||:||:...|:|||||.....
Mosquito   127 SCGI--QSYVA-KIRGGQLAEIDEFPWMAMLLYERDNNALTQGCGGALISRTYVITAAHCVTGKN 188

  Fly    93 H-------LVARLGEYERTRSEECTGYYCNFRE--EHMVD----AGFKHKLYD--PNTHANDIAI 142
            .       ...||.||....:.:|. |..:.::  :.|:|    |...|..||  .:...:|||:
Mosquito   189 FQQTKGRLKFVRLREYNIHTNPDCV-YENDLKDCSDDMIDLVPQAVIPHPEYDSESSNQQHDIAL 252

  Fly   143 LRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGKTQMESDS---DALQTLDIRRQPPD 204
            :|:.::..:.|.:|.||:. :..:.........|:.:|||:|.:..|:   |.|..:.::...|.
Mosquito   253 IRIEQTPPFTDFLRSICLP-EQNFESSATPGKKLSVSGWGRTDIFKDNLGPDVLSPIKLKLSLPY 316

  Fly   205 V----CAKFI---GQTIAGNQFCAGNWDS-NLCNGDSGGPLGAVITHKNTQRFVQ--VGIASYTN 259
            |    |:|..   ...:...|.|||...: :.|.||||.||.:.    :.:|.:.  .||.|...
Mosquito   317 VEREKCSKTFRPWSFALGPGQMCAGGERAKDTCAGDSGSPLMSY----DMKRAIWYITGIVSLGV 377

  Fly   260 RNC---QKASVFTDVLSHAEFILRVWRMY 285
            |.|   ....|:|:|..:..:|    :||
Mosquito   378 RGCGVEGLPGVYTNVHHYLPWI----KMY 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	71/268 (26%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	71/267 (27%)
CLIPB8	XP_312743.1	CLIP	41..95	CDD:288855
		Tryp_SPc	136..399	CDD:214473	71/268 (26%)
		Tryp_SPc	139..400	CDD:238113	71/270 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910