DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP011325

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_309327.4	Gene:	AgaP_AGAP011325 / 1270612	VectorBaseID:	AGAP011325	Length:	631	Species:	Anopheles gambiae

Alignment Length:	250	Identity:	91/250 - (36%)
Similarity:	129/250 - (51%)	Gaps:	21/250 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 RIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIAN-QHLVARLGEYERTRSE 107
            :|.||..|.....|||..|..|...|||||:||..:.||||||||... ..:..||||::.....
Mosquito   384 KIANGIDAILFQYPWMALLQDTELAFVCGGTLINKRYVLTAAHCFREKLSKISVRLGEFDLKSDI 448

  Fly   108 EC--TGYYCNFREEHM-VDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHY 169
            :|  .|..|....:.: |:...|||.|......||||::||:....|.:|:.|||:......|..
Mosquito   449 DCDKRGERCALPPQDIAVERTIKHKDYSARHKVNDIALIRLASEASYNENVMPICLPVSPEMRTV 513

  Fly   170 LDKIDLLTATGWGKTQMESDSDALQTLDIRRQPPDVCAKFIGQ-----TIAGNQFCA--GNWDSN 227
            .   ::...:|||.|:.::.||.||...:|:.|.|||.:.:.:     |:..:|.||  .|...|
Mosquito   514 K---EIYYVSGWGLTENDTSSDVLQVGLLRQLPNDVCQQLLQRKDKYVTVNSDQMCAIGANRTDN 575

  Fly   228 LCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQKAS---VFTDVLSHAEFIL 279
             |:|||||||..|..:   .||||.|:.||..|.|.|.:   |:|.|.::.::||
Mosquito   576 -CSGDSGGPLKTVAVN---ARFVQYGVVSYGLRTCGKETAPGVYTRVENYIDWIL 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	89/247 (36%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	89/246 (36%)
AgaP_AGAP011325	XP_309327.4	Tryp_SPc	44..287	CDD:238113
		Tryp_SPc	46..286	CDD:214473
		Tryp_SPc	384..625	CDD:214473	89/247 (36%)
		Tryp_SPc	385..625	CDD:238113	89/246 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BQ4K
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810