DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP007280

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_308537.4	Gene:	AgaP_AGAP007280 / 1269883	VectorBaseID:	AGAP007280	Length:	2275	Species:	Anopheles gambiae

Alignment Length:	357	Identity:	85/357 - (23%)
Similarity:	123/357 - (34%)	Gaps:	128/357 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LHSGCSQFLDPA--CG-------------IRTQSRT-------AYRIINGHTAKYNSSPWMVFLH 63
            :|..|     ||  ||             :||:...       :.||:.|..|...:.|::|.:.
Mosquito   901 VHVKC-----PAVRCGTSRMHEQHAARINVRTRREANESEIVESVRIVGGSHADPEAYPFIVGIF 960

  Fly    64 STTDMFVCGGSLITDKLVLTAAHC---FIANQHLVARLGEYERTRS----EECTGYYCNFREEHM 121
             ....:.||||:..:..:::||||   |  :||.........|.||    .:.|      |..||
Mosquito   961 -RDGKYHCGGSIYNEHWIISAAHCCDNF--DQHYFEVRSGMLRKRSFAPQVQIT------RVTHM 1016

  Fly   122 VDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKI------DLLTATG 180
            :    .|..|..:..|||||::|:.....|...:||||:...||.....|.|      .:.||.|
Mosquito  1017 I----VHHAYSSSLMANDIALMRVEHPFHYNRWVRPICMPERHRTTDDRDWIWGPKAGTVCTAIG 1077

  Fly   181 WGK---------------------TQMESDSDALQTLDIRRQPPDVCAKFIGQTIAGNQFCAGNW 224
            ||.                     .:.:||.|:|                        |.||...
Mosquito  1078 WGALRERGGAPDHLMQVSVPILGYCKHKSDRDSL------------------------QICAAEE 1118

  Fly   225 DS--NLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQKA---SVFTDVLSHAEFILR---- 280
            |.  :.|.||||||. ...:..|...:...|:.|: ...|.:|   .|:|.|....::|..
Mosquito  1119 DGGHDACQGDSGGPF-VCQSKSNPFEWYLAGVVSH-GEGCARAHEPGVYTRVALFIDWIAEKVNA 1181

  Fly   281 ----------------VWRMYGKGQTLPIPKK 296
                            :|   |.|..||..||
Mosquito  1182 PLPARTARADCPGMRCIW---GGGICLPPGKK 1210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	69/272 (25%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	68/271 (25%)
AgaP_AGAP007280	XP_308537.4	LDLa	698..733	CDD:238060
		Tryp_SPc	941..1175	CDD:214473	69/272 (25%)
		Tryp_SPc	942..1178	CDD:238113	69/274 (25%)
		LDLa	1196..1226	CDD:238060	7/18 (39%)
		LDLa	1510..1541	CDD:238060
		LDLa	1574..1609	CDD:238060
		DUF1986	1774..1887	CDD:286432
		LDLa	1999..2025	CDD:238060
		LDLa	2038..2071	CDD:238060
		LDLa	2107..2142	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910