DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP010635

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_307830.4	Gene:	AgaP_AGAP010635 / 1269219	VectorBaseID:	AGAP010635	Length:	569	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	81/285 - (28%)
Similarity:	125/285 - (43%)	Gaps:	57/285 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLH----STTDM-FVCGGSLITDKLVLTAAHCF- 88
            |..||.|...|... :..|::......||...|:    ::.|. :.||.:::...||:|||||.
Mosquito    34 DNECGERLVKRQEL-VKGGYSTHPGDWPWHAALYHRGFNSRDFEYACGSTIVHRYLVITAAHCVT 97

  Fly    89 -------IANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLS 146
                   |.:.::..|||.:....:||      .:.||..|.....|:.|.|.|..|||||||:.
Mosquito    98 FATSRRKIPSDNMQLRLGRFNLMNNEE------EYAEEFSVIDTIVHEGYRPTTLENDIAILRVE 156

  Fly   147 KSVVYRDNIRPICVVWDHRWRHYLDKIDLL-------TATGWGKTQMESDSDALQTLDIRRQPPD 204
            ..:::.|.|:|:|:     |:.. |..||.       |..|||.    |:::.:.|.....|.|.
Mosquito   157 IPIIFNDYIQPVCL-----WKRD-DGFDLPNVYNQPGTVVGWGL----SENNRIGTTLNEAQMPV 211

  Fly   205 V----C----AKFIGQTIAGNQFCAGNWD-SNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNR 260
            |    |    ..|.|:.:....||||..: :.:|||||||  |.....:|  |:...||.|:::.
Mosquito   212 VNSWTCLASDRAFFGRFLQSKAFCAGYKNGTGVCNGDSGG--GMFFQFQN--RWYLKGIVSFSSV 272

  Fly   261 N-----CQKASV--FTDVLSHAEFI 278
            |     |.....  |||...:.:::
Mosquito   273 NDYSGWCNLRQYIGFTDASQYIDWV 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	76/269 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	76/268 (28%)
AgaP_AGAP010635	XP_307830.4	Tryp_SPc	50..300	CDD:238113	76/268 (28%)
		Tryp_SPc	50..297	CDD:214473	76/266 (29%)
		Tryp_SPc	342..563	CDD:214473
		Tryp_SPc	342..563	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910