DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP013252

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_003436670.1	Gene:	AgaP_AGAP013252 / 11175997	VectorBaseID:	AGAP013252	Length:	597	Species:	Anopheles gambiae

Alignment Length:	329	Identity:	87/329 - (26%)
Similarity:	147/329 - (44%)	Gaps:	72/329 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FVGIILMF----QLLHSGCSQFLDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLH---STTDM 68
            |:.:|.:|    ::..:.....:...||.| :.:|.|.:.:|...|....||...::   .|...
Mosquito     8 FLALIAVFCAIGEVRKTNALDTVPLECGER-KVKTIYLVQHGTETKEGHWPWHTAIYHREQTNFE 71

  Fly    69 FVCGGSLITDKLVLTAAHCFIANQHLV------ARLGEYE----RTRSEECTGYYCNFREEHMVD 123
            :|||||::....:||||||...::.|:      .::|..:    ..||:|      :..|:.:|.
Mosquito    72 YVCGGSILDRNTILTAAHCLYTSRGLIKLDQLSVQVGRNQLSEASVRSQE------HHPEQLIVH 130

  Fly   124 AGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLL-----TATGWGK 183
            .||     .||:..:|||:::|:..:.....::|:| :|...     ..:||:     |..|:|.
Mosquito   131 PGF-----SPNSVTDDIALIKLATDITMTRYVQPVC-LWSLE-----PNLDLIVGRNGTVVGFGL 184

  Fly   184 TQMESDSDALQTLDIRRQPPDVC----AKFIGQTIAGNQFCAGNWDS-NLCNGDSGGPLGAVITH 243
            |:.:..||.|:...|.......|    .:..|.|:..|.:|.|.... ::|||||||  |....|
Mosquito   185 TEHDRVSDYLRQAAIAVVDSWTCIESDRQVYGVTLTANMYCGGGKTGVSVCNGDSGG--GMFFEH 247

  Fly   244 KNTQRFVQVGIASY--TNRN---CQ--KASVFTDVLSHAEFILRVWRMYGKGQTLPIPKKPPT-- 299
            .:|. :|: |:.|:  ...|   |.  |.:|||||..:.::|         ||.:     .||
Mosquito   248 GDTW-YVR-GVVSFMPLRENVGLCDGTKYTVFTDVAKYRDWI---------GQNV-----NPTLA 296

  Fly   300 TTRP 303
            :|||
Mosquito   297 STRP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	71/263 (27%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	71/262 (27%)
AgaP_AGAP013252	XP_003436670.1	Tryp_SPc	47..287	CDD:214473	71/260 (27%)
		Tryp_SPc	48..287	CDD:238113	71/259 (27%)
		Tryp_SPc	334..575	CDD:214473
		Tryp_SPc	335..575	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910