DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and F11

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	325	Identity:	86/325 - (26%)
Similarity:	129/325 - (39%)	Gaps:	96/325 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GVPTFVGIILMFQLLH--SGCSQF------LDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLH 63
            |.||        ::||  .|.|.:      :|..|..:...    |::.|..:.:...||.|.||
Mouse   356 GSPT--------RILHGRGGISGYSLRLCKMDNVCTTKINP----RVVGGAASVHGEWPWQVTLH 408

  Fly    64 STTDMFVCGGSLITDKLVLTAAHCF--------------IANQHLVARLGEYERTRSEECTGYYC 114
             .:...:||||:|.::.:|||||||              |.||           :...|.|.:
Mouse   409 -ISQGHLCGGSIIGNQWILTAAHCFSGIETPKKLRVYGGIVNQ-----------SEINEGTAF-- 459

  Fly   115 NFREEHMVDAGFKHKLYDPNTHAN---DIAILRLSKSVVYRDNIRPICV--------VWDHRWRH 168
             ||.:.|:       ::|..|.|.   |||:|:|..::.|.|..||||:        |....|
Mouse   460 -FRVQEMI-------IHDQYTTAESGYDIALLKLESAMNYTDFQRPICLPSKGDRNAVHTECW-- 514

  Fly   169 YLDKIDLLTATGWGKTQMESD-SDALQTLDIRRQPPDVC-AKFIGQTIAGNQFCAG--NWDSNLC 229
                     .||||.|.:..: ...||...:.....:.| .::....|.....|||  ....:.|
Mouse   515 ---------VTGWGYTALRGEVQSTLQKAKVPLVSNEECQTRYRRHKITNKMICAGYKEGGKDTC 570

  Fly   230 NGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC---QKASVFTDVLSHAEFILRVWRMYGKGQTL 291
            .|||||||..    |....:..|||.|: ...|   ::..|:|:|..:.::||.      |.||:
Mouse   571 KGDSGGPLSC----KYNGVWHLVGITSW-GEGCGQKERPGVYTNVAKYVDWILE------KTQTV 624

Fly 292 291
Mouse 625 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	72/265 (27%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	71/264 (27%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..376	CDD:128519	7/27 (26%)
		Tryp_SPc	389..617	CDD:214473	72/265 (27%)
		Tryp_SPc	390..617	CDD:238113	71/264 (27%)
		Heparin-binding. /evidence=ECO:0000250	547..550		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910