DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and tmprss2.1

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_004912265.1	Gene:	tmprss2.1 / 101731874	XenbaseID:	XB-GENE-22065907	Length:	482	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	68/258 - (26%)
Similarity:	106/258 - (41%)	Gaps:	46/258 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHC----FIANQH 93
            ||..|:: ...||:.|..|.....||.|.| ...:..:||||:||...:||||||    :.:...
Frog   237 CGSSTKN-VGNRIVGGSQASLGDWPWQVSL-QFNERHICGGSIITPNYILTAAHCVEGVYSSPYP 299

  Fly    94 LVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPI 158
            ....:|...::     ||     ...:.|.:...|:.||..|..||||::||...:.....::|:
Frog   300 WTVYVGSLYKS-----TG-----GTRYSVKSLIGHQNYDTKTKNNDIALMRLKSPITLTSTVQPV 354

  Fly   159 C-----VVW---DHRWRHYLDKIDLLTATGWGKT-QMESDSDALQTLDIRRQPPDVCAKFI--GQ 212
            |     ::|   ...|           .:|||.| :..:.|..|....:.....|.|.:.:  ..
Frog   355 CLPNAGMLWTSGQSCW-----------TSGWGATIEGGTSSGVLNAAMVPLIDSDTCNRAVVYNG 408

  Fly   213 TIAGNQFCAGNWDSNL--CNGDSGGPLGAVITHKNTQRFVQVGIASYTN--RNCQKASVFTDV 271
            .:.....|||.....:  |.|||||||   :| |.:..:..||..|:..  .|..|..|:.::
Frog   409 AVTATMICAGYLRGGIDSCQGDSGGPL---VT-KTSSLWWLVGDTSWGTGCANMNKPGVYGNI 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	65/247 (26%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	64/246 (26%)
tmprss2.1	XP_004912265.1	LDLa	112..143	CDD:238060
		SRCR_2	148..241	CDD:373897	2/3 (67%)
		Tryp_SPc	248..474	CDD:238113	64/246 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000