DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	271	Identity:	76/271 - (28%)
Similarity:	119/271 - (43%)	Gaps:	43/271 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQH---- 93
            ||:.|...:  ||:.|.:|.....||.|.| ...|..:||||:|....::|||||...:..
Frog   251 CGLSTYGES--RIVGGSSASIGDWPWQVNL-QYDDTNLCGGSVIAANWIVTAAHCVQGDTSSPSL 312

  Fly    94 LVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPI 158
            ..|.:|:.:.....:.:.|        .||....|..|...|::||||:::|..|:.:....||:
Frog   313 WKAFIGKIKMPSYYDSSAY--------SVDRIIVHPDYSSQTNSNDIALMKLKTSIAFSSISRPV 369

  Fly   159 C-----VVWDHRWRHYLDKIDLLTATGWGKT-QMESDSDALQTLDIRRQPPDVCAKFI--GQTIA 215
            |     :.|:.....|:        :|||.| |..|.|..|:...:....|..|.:.|  ...|.
Frog   370 CLPNYGMQWEEGQPCYI--------SGWGTTSQKGSISSVLKYAMVPLISPTTCNQTIMYNGAIT 426

  Fly   216 GNQFCA----GNWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTN--RNCQKASVFTDVLSH 274
            .:..||    |..||  |.|||||||   :|..|:..:: ||..|:.:  .|..:..|:.::...
Frog   427 SSMICAGYPKGGVDS--CQGDSGGPL---VTKTNSLWWL-VGDTSWGDGCANVYRPGVYGNMTVF 485

  Fly   275 AEFILRVWRMY 285
            .::|....:||
Frog   486 LQWIYLQMQMY 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	70/251 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	69/250 (28%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055	2/3 (67%)
		Tryp_SPc	261..489	CDD:238113	69/250 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910