DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and corin

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_004911266.2	Gene:	corin / 100492163	XenbaseID:	XB-GENE-950958	Length:	1123	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	65/263 - (24%)
Similarity:	109/263 - (41%)	Gaps:	35/263 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQ----- 92
            ||.|..:|.:.||:.|.|::....||...|.|.....:||..||..|.|||.||||...:
Frog   871 CGRRPAARMSKRILGGRTSRPGRWPWQCSLQSDPSGHICGCVLIGKKWVLTVAHCFEGRESAAVW 935

  Fly    93 HLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRP 157
            .:|..:...:         :..:|.:..:|.....|..|:......||:|:.|::.:.....:||
Frog   936 KVVFGINNLD---------HPSDFAQTRLVKKIILHPRYNRAVVDYDISIVELNEDITETSYVRP 991

  Fly   158 ICVVWDHRWRHYLDKIDLLTATGWG----KTQMESDSDALQTLDIRRQPPDVCAKFIG-QTIAGN 217
            :|:....:   .::.......||||    |...:.....::.:.:.|     |..:.. :||...
Frog   992 VCLPTKGQ---LVEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLER-----CQSYFDMKTITSR 1048

  Fly   218 QFCAGNWDSNL--CNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQKA---SVFTDVLSHAEF 277
            ..|||.....:  |.|||||||   :..|...::...|:.|:.:....|.   .|:::|....|:
Frog  1049 MLCAGYESGTIDSCMGDSGGPL---VCEKPGGKWTLYGLTSWGSVCFSKVLGPGVYSNVSHFVEW 1110

  Fly   278 ILR 280
            |.|
Frog  1111 IER 1113

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	59/248 (24%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	58/247 (23%)
corin	XP_004911266.2	CRD_corin_1	213..341	CDD:143554
		LDLa	351..382	CDD:238060
		LDLa	384..418	CDD:238060
		LDLa	420..455	CDD:238060
		LDLa	465..492	CDD:238060
		CRD_corin_2	533..654	CDD:143579
		LDLa	659..693	CDD:238060
		LDLa	734..768	CDD:238060
		Tryp_SPc	883..1114	CDD:238113	60/251 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910