DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18636 and tmprss9

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_002940084.3	Gene:	tmprss9 / 100489279	XenbaseID:	XB-GENE-993973	Length:	1151	Species:	Xenopus tropicalis

Alignment Length:	309	Identity:	81/309 - (26%)
Similarity:	118/309 - (38%)	Gaps:	51/309 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVAR 97
            ||.|...:...||:.|..|.....||.|.|....:.| ||.::|.||.:::|||||...|.....
Frog   223 CGTRPAMQKTNRIVGGSDATKGEFPWQVSLRENNEHF-CGATVIGDKWLVSAAHCFNDFQDPAVW 286

  Fly    98 LGEYERTRSEECTGYYCNFREEHMVDAG----FKHKLYDPNTHANDIAILRLSKSVVYRDNIRPI 158
            :. |..|.|...|       :...|.|.    .||..|||:|...|:|:|.|...:.:....:|:
Frog   287 VA-YIATTSLSGT-------DSSTVKATIRNIIKHPSYDPDTADYDVAVLELDSPLKFNKYTQPV 343

  Fly   159 CVVWDHRWRHYLDKIDLLTATGWGKTQMESDS----DALQTLDIRRQPPDVCAKFIGQTIAGNQF 219
            |:...   .|..........||||  .::.|:    :.||...:......:|.......:.....
Frog   344 CLPDP---THVFPVGKKCIITGWG--YLKEDNLVKPEVLQKATVAIMDQSLCNSLYSNVVTERML 403

  Fly   220 CAGNWDSNL--CNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQKA---SVFT---------- 269
            |||..:..:  |.|||||||   :..:.:.:|...||.|: ...|.:|   .|:.
Frog   404 CAGYLEGKIDSCQGDSGGPL---VCEEPSGKFFLAGIVSW-GVGCAEARRPGVYVRVSKIRNWIL 464

  Fly   270 DVLS-------HAEFILRVWRMYGKGQTLPIPKKPPTTTRPPTWWHTTR 311
            |::|       ...|........|..:|   .....||.||.|...|||
Frog   465 DIISSSVAADPQTSFTTTTTTTTGGRKT---TNAKTTTARPFTKHSTTR 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	67/263 (25%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	66/262 (25%)
tmprss9	XP_002940084.3	SEA	60..156	CDD:396113
		LDLa	186..221	CDD:238060
		Tryp_SPc	234..463	CDD:214473	65/246 (26%)
		Tryp_SPc	547..774	CDD:238113
		LDLa	871..906	CDD:238060
		Tryp_SPc	919..1145	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910