DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and tmprss15

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_001919639.2	Gene:	tmprss15 / 100148042	ZFINID:	ZDB-GENE-091204-83	Length:	990	Species:	Danio rerio

Alignment Length:	290	Identity:	73/290 - (25%)
Similarity:	116/290 - (40%)	Gaps:	59/290 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIR-----------TQSRTAYRIINGHTAKYNSSPWMVFL-----HSTTDMFVCGGSLITDKLV 81
            ||:|           |..:...|::.|..|:..:.||||.|     |:      ||.:||..:.:
Zfish   725 CGVRKVPSKSKIIEETDGKKEGRVVGGQDAQRGAWPWMVSLQWLGGHA------CGATLIDREWL 783

  Fly    82 LTAAHCFIANQHLVARLGEYERTRSEECTGYYCNF------REEHMVDAGFKHKLYDPNTHANDI 140
            :|||||.....   .:|..:...     .|.:..|      ::...||....||.|:..|..:|.
Zfish   784 ITAAHCVYGRN---VQLSNWAAV-----LGLHAQFETINPNKQVFSVDQVIMHKHYNKRTKESDF 840

  Fly   141 AILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGKTQMESDS----DALQTLDIRRQ 201
            |::.|...|.|.|.::|||:  .....|:.:......| |||   :.|:|    |.||...:...
Zfish   841 ALMHLKTPVSYTDYVQPICL--PDPGAHFEEGRKCFIA-GWG---LLSESGLKADVLQQAVVPLL 899

  Fly   202 PPDVCAKFIGQ-TIAGNQFCAGNWDSNL--CNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC- 262
            ....|.:::.: .......|||..:..:  |.|||||||..    :....:|.||..|: ...|
Zfish   900 SNTQCQEWLPEYNFTERMMCAGYAEGGVDTCQGDSGGPLMC----EEEGHWVLVGATSF-GIGCG 959

  Fly   263 --QKASVFTDVLSHAEFILRVWRMYG--KG 288
              |:...:..|....:::....|:|.  ||
Zfish   960 RPQRPGAYARVSQFVDWVAENRRLYSDWKG 989

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	65/254 (26%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	64/253 (25%)
tmprss15	XP_001919639.2	SEA	19..>89	CDD:279699
		LDLa	142..175	CDD:238060
		CUB	183..288	CDD:238001
		MAM	302..457	CDD:279023
		MAM	302..457	CDD:99706
		CUB	477..586	CDD:238001
		LDLa	596..630	CDD:238060
		SRCR_2	653..728	CDD:295335	2/2 (100%)
		Tryp_SPc	747..977	CDD:214473	65/254 (26%)
		Tryp_SPc	748..980	CDD:238113	64/256 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910