DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and proc.2

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001120289.1	Gene:	proc.2 / 100145345	XenbaseID:	XB-GENE-5882297	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	70/249 - (28%)
Similarity:	111/249 - (44%)	Gaps:	34/249 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 RIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVARLGEYERTRSEE 108
            ||:.|...:....||.|.:.:......||||||:.:.||:|||||.:.......:|:|:..|.:
Frog   435 RIVGGMRCELGQCPWQVLIRNNRGFGFCGGSLISSRWVLSAAHCFESQIPHHVTIGDYDTYRRD- 498

  Fly   109 CTGYYCNFREEHMVDA--GFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLD 171
                    .:|..:..  .|.|..|....:.:|||:|.|....::.:..||||:.     ...|.
Frog   499 --------MDEQKIAVLQVFSHPNYLAEFYDHDIALLFLRSPAMFGEYSRPICLP-----NPGLG 550

  Fly   172 KIDLLT-------ATGWGKT-QMESDSDALQTLDIRRQPPDVCAKFIGQTIAGNQFCAGNWD--S 226
            |  :||       .:|||.| |....:..|..:.:.....:.|.......:.||.||||..:  .
Frog   551 K--MLTQEGQTGQVSGWGATRQFGPYTRFLLKVRLPIVSQETCMASTENILTGNMFCAGYKEGVK 613

  Fly   227 NLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQKA--SVFTDVLSHAEFI 278
            :.|:||||||. ||:.|   ..:..||:.|:.:...:|.  .|:|.|.::..:|
Frog   614 DACSGDSGGPF-AVLFH---DTWFLVGVVSWGDGCAEKGKYGVYTRVANYMPWI 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	69/247 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	68/246 (28%)
proc.2	NP_001120289.1	GLA	19..80	CDD:214503
		EGF_CA	81..117	CDD:238011
		FXa_inhibition	123..160	CDD:373209
		Tryp_SPc	436..666	CDD:238113	69/248 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910