DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	299	Identity:	77/299 - (25%)
Similarity:	115/299 - (38%)	Gaps:	82/299 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQH--- 93
            |||.|  .:.:.||:.|:.:.....||.|.||...: .:||||:||.:.:||||||.....:
Zfish   287 ACGSR--PKFSARIVGGNLSAEGQFPWQVSLHFQNE-HLCGGSIITSRWILTAAHCVYGIAYPMY 348

  Fly    94 --LVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIR 156
              :.|.|.|..           .|..:...|:....|..|.|....:|||:::|::.:.:...:.
Zfish   349 WMVYAGLTELP-----------LNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVE 402

  Fly   157 PICVVWDHRWRHYLDKIDLLTATGWGKTQMESDSDALQTLDIRRQP---------PDVCAKFIGQ 212
            |||:   ..:....:...:...:|||.|  |...||..:......|         |:|   :.|.
Zfish   403 PICL---PNFGEQFEDGKMCWISGWGAT--EDGGDASVSQHCASVPLISNKACSQPEV---YQGY 459

  Fly   213 TIAGNQFCAGNWD--SNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQKASVFTDVLSHA 275
            ..|| ..|||..|  ::.|.|||||||.                       |:.:|
Zfish   460 LTAG-MICAGYLDGGTDSCQGDSGGPLA-----------------------CEDSS--------- 491

  Fly   276 EFILRVWRMYGK---GQTLPIPKKPPTTTR---PPTWWH 308
                 :|::.|.   ||......||...||   ..||.|
Zfish   492 -----IWKLVGATSWGQGCAEKNKPGVYTRITQSLTWIH 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	62/249 (25%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	61/248 (25%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	4/6 (67%)
		Tryp_SPc	298..525	CDD:238113	71/284 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910