DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33301 and CG6830

DIOPT Version :9

Sequence 1:	NP_001285793.1	Gene:	CG33301 / 2768917	FlyBaseID:	FBgn0053301	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	117/426 - (27%)
Similarity:	207/426 - (48%)	Gaps:	34/426 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLPTWLTAAYLQPRLRAYCQDDRLQVLRIWAKPATGKGENFVGVMTRIYVDYQLGDGSVVNKTYI 65
            ::|.||.....:..|.|.. |...:::....|||...|||:..:|.||.:|.:|.|.|....:::
  Fly    45 LVPKWLNQTQFEELLAADV-DQFSKIVGFRVKPAMAPGENYATLMLRISIDVELTDKSTKLVSFM 108

  Fly    66 VKQALSAEVPQAEVFFEY-ELYTREMDMYEFILPKLKELLQEAGLDQKLTADAITVD-----REY 124
            :|  :..:.||.|..... ..:|.|...|..||||::||.:..|||.|....|..:|     :..
  Fly   109 MK--VPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEPKVA 171

  Fly   125 NTMILEDLAPYKFVNADRVKQLDMAHTELTLEMLAKFHAASIVLQERH---PNLLTKCFYTHFFS 186
            ||:::.||....|.|.:|::.|::..|:..|..||:||||...:.:.|   |::    |......
  Fly   172 NTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDI----FVNGVMG 232

  Fly   187 RDKKAYSVVFAGLFKAF-LRFIDGQPNLK--EAYGDKLHK----LRTHIMEYGARAYDVGESDLK 244
            .:|:|......|:..:| ..|:......|  |.|.:||.|    |....|:.|.    |..::..
  Fly   233 NNKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMKLGI----VDPNEFN 293

  Fly   245 TLNHGDCWTTNIMFQYDDAGEPRSVVAIDFQFSNCTSPTIDLHYFFTTSLREEVGDKESE---LV 306
            .|||||||..|::|:.:.:|:...:|.:|||.....||.:||.||..:|:  ::..|.|.   .:
  Fly   294 ALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSV--QIDYKLSHFDFFI 356

  Fly   307 EHHYKALKANLEKFSYKGSLPTLQE-YRLQFERRRFMSLLAHMFKPCMIYNGSEETSDFSSLYAE 370
            .|:.:||..:|....:.|..|:|:| :|...:...::........|.::.:.: :::.|.:..::
  Fly   357 RHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPT-QSATFDNFMSD 420

  Fly   371 SPEGLRYQKSVYASEAVIRSATKLLAILDAKGLLEL 406
            |.:|:.::.|:||::.......::|..||.:|.||:
  Fly   421 SADGVSFRGSLYANKRCQEYIERILPWLDNRGFLEV 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33301	NP_001285793.1	EcKinase	37..322	CDD:281023	90/303 (30%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	90/303 (30%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459388
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850