DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33301 and CG31099

DIOPT Version :9

Sequence 1:	NP_001285793.1	Gene:	CG33301 / 2768917	FlyBaseID:	FBgn0053301	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_733099.1	Gene:	CG31099 / 326117	FlyBaseID:	FBgn0051099	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	105/422 - (24%)
Similarity:	190/422 - (45%)	Gaps:	47/422 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LPTWLTAAYLQPRLRAYCQDDRLQVLRIWAKPATGKGENFVGVMTRIYVDYQLGDGSVVNKTYIV 66
            :|.|:::..|...:.:..:|. :|:..:.......:..|.. |:..|.|..||.|.::....:::
  Fly     6 IPDWVSSLSLNQAVHSVLEDG-VQITSVIPSVHLIQFRNCT-VLLPIQVKVQLRDFTMKKLFFLL 68

  Fly    67 KQALSAEVPQAEVFFEYELYTREMDMYEFILPKLKELLQEAGLDQKLTADAITVDREYNT--MIL 129
            |.....:: ||.|..:.:::.||..:|..:||||:|:.:|.|........|..:|.....  ::|
  Fly    69 KAQHGTDI-QAMVMNQLKMFQREHQVYHNVLPKLEEIYREVGKKVSFGPRAFRLDYSIGVQYVLL 132

  Fly   130 EDLAPYKFVNADRVKQLDMAHTELTLEMLAKFHAASIVLQERH---PNLLTKCFYTHFFSRDKKA 191
            |||....:.|.:|....:....:..|:.||:|||||.|..|:|   .|||....||       ||
  Fly   133 EDLKAKSYKNVERQAGFNKLCLKQVLKKLAQFHAASAVCVEKHGAFSNLLVNGVYT-------KA 190

  Fly   192 YSVVFAGL-----FKAFLRFIDGQPNLKEAYGDKLHK----LRTHIMEYGARAYDVGESDLKTLN 247
            ...|...|     |.:.||        :...||..||    ....:::...:.:....::...||
  Fly   191 NESVLQELNDPEIFLSQLR--------RWRLGDHFHKRLVEKEKDLVDGLLKLHSPDSNEFNVLN 247

  Fly   248 HGDCWTTNIMFQYDDAGEPRSVVAIDFQFSNCTSPTIDLHYFFTTSLREEVGDKE-SELVEHHYK 311
            |.|||..|:||::||:|.......:|:|.....||.|||:|...:|..:::...: ..:|::::.
  Fly   248 HSDCWVNNVMFKFDDSGHVEDTALLDYQLVKYGSPAIDLYYTILSSAEKDIKLAQFDNMVQYYFY 312

  Fly   312 ALKANLEKFSYKGSLPTLQEYRLQFERRRFMSLLAHMF----KPCMIYNGSEETSDFSSLYAESP 372
            .|..||:..::.||||.||..|....:.   .|.|::.    .|..:.|..|:  :.:..||.
  Fly   313 HLLDNLKALNFGGSLPQLQHIRDALNKN---GLAAYVVVTRALPITMMNQFED--EVNERYAS-- 370

  Fly   373 EGLRYQKSVYASEAVIRSATKLLAILDAKGLL 404
               :.:.:::.|...|::...:|..::.:.||
  Fly   371 ---KMKCAMFTSRKYIQAIKDILPWMEERSLL 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33301	NP_001285793.1	EcKinase	37..322	CDD:281023	81/299 (27%)
CG31099	NP_733099.1	EcKinase	44..323	CDD:281023	80/295 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850