DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33301 and CG31380

DIOPT Version :9

Sequence 1:	NP_001285793.1	Gene:	CG33301 / 2768917	FlyBaseID:	FBgn0053301	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_733121.1	Gene:	CG31380 / 318701	FlyBaseID:	FBgn0051380	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	136/414 - (32%)
Similarity:	231/414 - (55%)	Gaps:	26/414 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LPTWLTAAYLQPRLRAYCQDDRLQVLRIWAKPATGKGENFVGVMTRIYVDYQLGDGSVVNKTYIV 66
            :..||||.||:..||.|.|::.|:|..:...||.|||||:..::|||::.|    .|:|.:..|.
  Fly     1 MAAWLTAEYLEAALRRYYQNNELRVESMVINPALGKGENYGAILTRIHLVY----SSIVEEHLIA 61

  Fly    67 KQALSAEVPQAEVFFE---YELYTREMDMYEFILPKLKELLQEAGLDQKLTADAITVDREYNTMI 128
            |..|  |...||...:   |::|.||:::||.:||||:||   ||  ::|....:.:||:...:|
  Fly    62 KTVL--EYEDAETKMKKAPYDIYNRELEIYEQVLPKLQEL---AG--EQLCPKILHIDRQRGALI 119

  Fly   129 LEDLAPYKFVNADRVKQLDMAHTELTLEMLAKFHAASIVLQERHPNLLTKCF----YTH-FFSRD 188
            :|||:...||.|.|:::||..|..|.|..|||..|||.||:.   |||...|    |.. ||:|.
  Fly   120 MEDLSYKGFVMAPRLQRLDEQHVSLVLRKLAKMQAASAVLEN---NLLENNFSLTEYDKGFFNRY 181

  Fly   189 KKAYSVVFAGLFKAFLRFIDGQPNLKEAYGDKLHKLRTHIMEYGARAYDVGESDLKTLNHGDCWT 253
            .:::|..|.|..|:...::..|... |.:...|.:|..:.|..|.|.:...::.:..|.|||.||
  Fly   182 TESFSAYFLGCLKSCANYLKTQAGY-EHHAKLLDELAPYYMGLGLRCFKQEQTHINVLTHGDLWT 245

  Fly   254 TNIMFQYDDAGEPRSVVAIDFQFSNCTSPTIDLHYFFTTSLREEV-GDKESELVEHHYKALKANL 317
            .|:||:| :||.|..|:.||||::...|||:|:|:...||..|:| .:.:.::...::......|
  Fly   246 NNMMFKY-EAGVPSDVLLIDFQYAFWGSPTLDIHHLLNTSAVEQVRSELQMKMRGVYHDVFVGEL 309

  Fly   318 EKFSYKGS-LPTLQEYRLQFERRRFMSLLAHMFKPCMIYNGSEETSDFSSLYAESPEGLRYQKSV 381
            ::..:||. ||:.:::.|:.|::||.::...:....::.|..|..:||::|.::.|.|:..::.:
  Fly   310 QRLGFKGQRLPSRKQFHLESEQKRFYAVHCGLLLLPVLLNTDETDADFAALLSDQPRGMDMKRRL 374

  Fly   382 YASEAVIRSATKLLAILDAKGLLE 405
            |.:..:..|..:::...:.:|||:
  Fly   375 YLNPGIQDSIKQMVKHFELEGLLD 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33301	NP_001285793.1	EcKinase	37..322	CDD:281023	101/293 (34%)
CG31380	NP_733121.1	EcKinase	36..314	CDD:281023	101/293 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449880
Domainoid	1	1.000	166	1.000	Domainoid score	I7989
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	1	1.000	-	-		H115919
Inparanoid	1	1.050	53	1.000	Inparanoid score	I4082
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	11	10.910