Protein Alignment CG33310 and ATP4B

DIOPT Version :10

• Sequence 1: NP_995718.2
• Gene: CG33310 / 2768910
• FlyBaseID: FBgn0053310
• Length: 876
• Species: Drosophila melanogaster
• Sequence 2: NP_000696.1
• Gene: ATP4B / 496
• HGNCID: 820
• Length: 291
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 56/326 - (17%)
• Similarity: 114/326 - (34%)
• Gaps: 111/326 - (34%)

  Fly   583 EWRRLFFNKIHGKYKLRRPSHWLY-TLVFSVLYILFVIIFSMAWFDFIKD-DASRKVPMIKMAQP 645
            |::|..:|...|:...|..|.|:: :|.:...|::...:|::..:..::. |........::..|
Human    16 EFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLYVLMQTVDPYTPDYQDQLRSP 80

  Fly   646 FISFTP---------------------------------IGPRTNPKAV-----------SFDPR 666
            .::..|                                 ..|.....::           ||...
Human    81 GVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGYSPAAQEDSINCTSEQYFFQESFRAP 145

  Fly   667 NSTEVMEKYAGIMALLEKYGDYGHNPRFGTCT--ANEKFGYPSGEPCVFLKVNRIIGF----KTE 725
            |.|:...|:...|              ...|:  |:..||:..|:||..:|:|||:.|    .:.
Human   146 NHTKFSCKFTADM--------------LQNCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSNGSA 196

  Fly   726 PYINSDELVKAKIDEVEFTALKRLLENTTTEEGHLNRTWITCRSDKDKNVLIEFHPEPAIRTEYT 790
            |.::.     |.:|:..                           :..:.:.::::|.....:
Human   197 PRVDC-----AFLDQPR---------------------------ELGQPLQVKYYPPNGTFS--- 226

  Fly   791 DIEEKIEYIANEGKKSFFGPNDVNRIVALKIKNLKANERVHINCKMWAQNI--HHRKEGY-GQVS 852
                 :.|....|||:  .|:..|.:||.|:.|:..|..|.|.||:.|:::  ::..:.| |:|.
Human   227 -----LHYFPYYGKKA--QPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVE 284

  Fly   853 F 853
            |
Human   285 F 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33310	NP_995718.2	Na_K-ATPase	<703..846	CDD:471796	30/148 (20%)
ATP4B	NP_000696.1	Na_K_ATPase_bet	2..291	CDD:273446	56/326 (17%)
		immunoglobulin-like	194..291		24/134 (18%)