Protein Alignment CG3857 and Smg9

DIOPT Version :10

• Sequence 1: NP_996330.1
• Gene: CG3857 / 2768908
• FlyBaseID: FBgn0023520
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_082323.1
• Gene: Smg9 / 71997
• MGIID: 1919247
• Length: 520
• Species: Mus musculus
• Alignment Length: 507
• Identity: 117/507 - (23%)
• Similarity: 197/507 - (38%)
• Gaps: 150/507 - (29%)

  Fly    46 RDREQ-ETWDRER---DKD-------------RKLERDREAEPSPSCYPDTPPA---LKTMIVNR 90
            |:|:. ..|:|||   .:|             .|...:|..:|.||..|..|||   |:..||
Mouse    37 RERDYIAPWERERRDGSEDPSTNVMQKTPIILSKPPAERSKQPPPSTAPAAPPAPAPLEKPIV-- 99

  Fly    91 TGEVRPADRCQMPLAGGALVQGSGQLSAVPSSSVCAALVSSVPTSRDKGSCSG------------ 143
              .::|.:..:.|:||.......|.....|::           .:..||...|
Mouse   100 --LMKPREEGKGPVAGTGASTPEGTAPPPPTA-----------PAPPKGEKEGQRPTQPVYQIQN 151

  Fly   144 -GAGTAGTSAGAPNALQ-ELQPPRMNRPTPLIVANGIFNANARKLFHKTNTDFTVIGVLGGQSSG 206
             |.|||..:|..|...| :|.||...:.:..:|.:.:...::...:....||..|:||||.|.:|
Mouse   152 RGMGTAAPTAMDPVVGQAKLLPPERMKHSIKLVDDQMNWCDSAIEYLLDQTDVLVVGVLGLQGTG 216

  Fly   207 KSTLLNLLAAERSLDYDYYQHLFSPEADECIFATR---HKLKPNNGQKSILRPRTETLQFFITRE 268
            ||.:::||:|.            :||.|:..:..|   .::|...|.      :|..:.||||:|
Mouse   217 KSMVMSLLSAN------------TPEEDQRAYVFRAQSAEMKERGGN------QTSGIDFFITQE 263

  Fly   269 RHILLDTPPLMP-------VGKD----------SDHQDLYSLGTMAQLLSVCHILILVIDGLA-L 315
            |.:.|||.|::.       :..|          ..:.::.||...|.|.:|||::|:|.|... |
Mouse   264 RIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTYVEMQSLQIAAFLFTVCHVVIVVQDWFTDL 328

  Fly   316 EQLRLINAALRLRPTLHCKGYV----------RDHMPQVVFVRARAHRIDF---EIQQRE-RLDK 366
            ...|.:..|..::|:.....:.          .::.|.:||::.:|.|.||   :::|.. .:|:
Mouse   329 SLYRFLQTAEMVKPSTPSPSHESSSSAGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHLMIDQ 393

  Fly   367 KLAYLYGPTGLPIYRGRG------------------DARCLNTFLLPEVSS------------NK 401
            .:|:.:       .|.:|                  ||. :|.||:|.:.|            ..
Mouse   394 LMAHSH-------LRYKGTLSMLQCNVFPGLPPDFLDAE-VNLFLVPFMDSEAENENPPRAGPGS 450

  Fly   402 ATAF--------HSCLGELVRQFRERILGCTRISMCHTSTELSEAIWFEILA 445
            :..|        |.....||.:.|.:::...|..:.||.  |:|..||...|
Mouse   451 SPLFSLLPGYRGHPSFQSLVSKLRSQVMSMARPQLSHTI--LTEKNWFHYAA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3857	NP_996330.1	P-loop containing Nucleoside Triphosphate Hydrolases	188..>318	CDD:476819	43/150 (29%)
Smg9	NP_082323.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..143		28/120 (23%)