DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3857 and smg9

DIOPT Version :9

Sequence 1:	NP_996330.1	Gene:	CG3857 / 2768908	FlyBaseID:	FBgn0023520	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_001923815.2	Gene:	smg9 / 562557	ZFINID:	ZDB-GENE-030131-9385	Length:	505	Species:	Danio rerio

Alignment Length:	528	Identity:	123/528 - (23%)
Similarity:	205/528 - (38%)	Gaps:	145/528 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RRRFRNKKRDEA---CSGLLAP------VTIARR----EDAARMMQ--PKILLKKDRDREQ---- 50
            |||.|.::||.|   ...|..|      |...||    |....::|  |.||.|...:|.:
Zfish    16 RRRRRRRERDPAGPPGQNLSGPSRDRDYVPRERRDGSEESTGPLLQKTPIILAKPPGERSKASAP 80

  Fly    51 ETWDRERDKDRKLERDREAEPSPSCYPDTPPALKTMIVNRTGEVRPADRCQMPLAGGALVQGSGQ 115
            .:.....:|...|.:.|:....|...||.||:...                   ||.|.::..||
Zfish    81 ASGPPSLEKPIMLIKTRDEGGKPGNPPDIPPSASG-------------------AGTAKMEREGQ 126

  Fly   116 LSAVPSSSVCAALVSSVPTSRDKGSCSGGAGTAGTSAGAPNALQELQPPRMNRPTPLIVANGIFN 180
            ....|...:         .:|..||.:.| |......|.    .:|.||...:.:..:|.:.:..
Zfish   127 RPTQPVYQI---------QNRGMGSAASG-GAVDPVIGQ----TKLLPPEKMKHSIKLVDDQMNW 177

  Fly   181 ANARKLFHKTNTDFTVIGVLGGQSSGKSTLLNLLAAERSLDYDYYQHLFSPEADECIFATR---H 242
            .::...:.:..||..|:||:|.|.:||||:::||:|.            |||.|:..:..|   .
Zfish   178 CDSAMEYLRDQTDMLVVGVIGLQGTGKSTIMSLLSAN------------SPEEDQRAYVFRAQTQ 230

  Fly   243 KLKPNNGQKSILRPRTETLQFFITRERHILLDTPPLMP-------VGKD----------SDHQDL 290
            ::|...|.:|      ..:.|:||:||.|.|||.|::.       :..|          ..:.::
Zfish   231 EIKERAGNQS------SGIDFYITQERVIFLDTQPVLSPSILDHLINNDRKLPPEYNLPHTYVEM 289

  Fly   291 YSLGTMAQLLSVCHILILVIDGLA-LEQLRLINAALRLRPTLHCKGY----------VRDHMPQV 344
            .||...|.|.:|||::|::.|... :...|.:..|..|:|:.....:          ..::.|.:
Zfish   290 QSLQITAFLFTVCHVVIVIQDWFTDINLYRFLQTAEMLKPSTPSASHDSTGSSGPDDGSEYYPHI 354

  Fly   345 VFVRARAHRIDFEIQQRERL----DKKLAYLYGPTGLPIYRGR----------GDARC-----LN 390
            ||::.:|.|.:|..:..:::    ||.:|:.:..     |:|.          |.:|.     :|
Zfish   355 VFLQNKARREEFCPRNLKKMHMAVDKLMAHSHLK-----YKGTLSMLDCNIFPGLSRDYMETEVN 414

  Fly   391 TFLLPEVSSNKATAF------------------HSCLGELVRQFRERILGCTRISMCHTSTELSE 437
            .||||.:.::...|.                  |.....||.:||.:||..:|..:.||.  |:|
Zfish   415 LFLLPLMENDGEDALTRAGSGPPLFSLLPGYRGHPNFSSLVSKFRSQILAMSRSQLSHTI--LTE 477

  Fly   438 AIWFEILA 445
            ..||...|
Zfish   478 KNWFHYAA 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3857	NP_996330.1	P-loop_NTPase	188..>318	CDD:304359	42/150 (28%)
smg9	XP_001923815.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594885
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I5279
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1436399at2759
OrthoFinder	1	1.000	-	-		FOG0008337
OrthoInspector	1	1.000	-	-		oto40039
orthoMCL	1	0.900	-	-		OOG6_105416
Panther	1	1.100	-	-	LDO	PTHR14270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2801
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.930