Protein Alignment CG42271 and Prex2

DIOPT Version :9

• Sequence 1: NP_996434.2
• Gene: CG42271 / 2768892
• FlyBaseID: FBgn0259166
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: NP_001380724.1
• Gene: Prex2 / 312912
• RGDID: 1307865
• Length: 1598
• Species: Rattus norvegicus
• Alignment Length: 1443
• Identity: 268/1443 - (18%)
• Similarity: 467/1443 - (32%)
• Gaps: 477/1443 - (33%)

  Fly    18 RFDKEGLLIITDRQEGFLWRSSEVR------VERWCKLRGNLLFYLKDKD-----PKSAVAG--- 68
            :|..|.:|......:|..:..||::      |..:|:|.......::|||     .||.|..
  Rat   444 QFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKL 508

  Fly    69 ---LLVLENCRARIQNEERDSEGYVFDL---------------DFKDSP-SERFITRSSAERLAW 114
               |:...:||.|       .|..:|.:               :|||.| ..||......|
  Rat   509 IDWLIAQGDCRTR-------EEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEME---- 562

  Fly   115 VQCIEHASSEKLNALIRQLK--EQIVSQSRQPSSGASSSMGNHIDLGMPLEQQMQE---QLQLHG 174
                  .|:.|...:...||  |.::::|....|...|       .|..||.:.:.   :|...|
  Rat   563 ------GSNMKHRLMKHDLKVVENVIAKSLLIKSNEGS-------YGFGLEDKNKVPIIKLVEKG 614

  Fly   175 QPAEELSVPVPTEVVA---------PFEELDL-------SELPICETALSCDTLPLDTLGRPPNP 223
            ..||...:.|..::.|         ||.|:|.       |..|:   .:...|.|.:|:..|.:.
  Rat   615 SNAEMAGMEVGKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPL---RVLVSTKPRETVKIPDSA 676

  Fly   224 QVVCSLLPTAGEDCVWREHA--RTELQERTRTPQFLCTMRFQRSAGLSASTRLRFSVFDVRERMT 286
            ..:...:...|...|   ||  |..:..........|.::..   |::.|.....||
  Rat   677 DGLGFQIRGFGPSVV---HAVGRGTVAAAAGLHPGQCIIKVN---GINVSKETHASV-------- 727

  Fly   287 LTAVPLGHAEVALGVIQDTSRLRLPLTSPRGECGFITLASWSPDAAVEPGQSGNGPPRSST-QLF 350
                 :.|       :....:.:.|:.....:..:.:|.|...|..    :|.:.||.... .:|
  Rat   728 -----IAH-------VTACRKYKRPMKQDSIQWVYDSLESAQEDIQ----KSHSKPPGDEAGDVF 776

  Fly   351 DGSAGAGGATTSSRRAHRRTQSLPPKLGVRLFVP-QQCGLQRVCSNPRLR---TYRLHSSLGADI 411
            |                .:.:.:..|......:. ::..:.....|..|.   .|...|:.|...
  Rat   777 D----------------CKVEDVMDKFNTLAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKC 825

  Fly   412 SVQETLLESRLCCQLPQQLLSIWIQREKELLQEISGMGELSG------EWRWRQM--NLLEEHLR 468
            :|.|.::|.:....|..::|....:.::..:|..:.:..|:.      :.::..|  ..:|....
  Rat   826 NVVEKMVEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERVEHVCH 890

  Fly   469 LLKDYSQAKQNIQQLARDGVSFKRSSAKAD--ESLEFLPVNLHVQRM---------------WAQ 516
            .:..|.:..:.::.  |...:||::.||..  .|.:|.|.|.||..|               ..|
  Rat   891 RISSYGRFSRVLKN--RAWPTFKQAKAKMSPLHSSDFCPTNCHVNVMEVSYPKASASLGSAFGVQ 953

  Fly   517 NDTLQRR-----------GLLD--------VVTVGAFTRHDPKGRKCG-----GLIKLLQESKSW 557
            .|:.:..           |.|.        :.|:.|     |.|...|     ||..||:|.
  Rat   954 LDSRKHNSHDKENRSADPGKLSPMVYIQHTITTMAA-----PSGLSLGHKDGHGLRYLLKEE--- 1010

  Fly   558 KLEQSNACKVQAANDAVQATKQLRKEIVELMSQLLQLASRRSSMDMMPLCNQMVARTRTLLN--L 620
            .||                |:.:..::         |...::::..:.:|   |.:...||:  .
  Rat  1011 DLE----------------TQDIYHKL---------LGKLQTALKEVEMC---VCQIDDLLSSIT 1047

  Fly   621 WEPSIVEEAVAFIERHRIIEEPENVLMEPMSPFRKITQQLTALELKSPELEDFATPVVAPPDLWP 685
            :.|.:..:...::    |..:.:|...|..|       :.....:...|.||
  Rat  1048 YSPKLERKTTEYV----IPTDSDNEKGERNS-------KRVCFNVAGDEQED------------- 1088

  Fly   686 RGQPPLMRSNSWHPSNSSPSSSLDIRAIDSLQHVVKCYNDHLRSLEQGRQPGRQADDEEQEEATY 750
            .|...:...:|:...||:.:|.....:|.|.|.....::|.:              |...|..|
  Rat  1089 SGHDTVSNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEM--------------DSGDELPT- 1138

  Fly   751 QSLPVAWQTQSEVSAGTQIPPSDNPADLSVLQL-IDLDEI-----GRQAQRQRHHQPPAGFLDTK 809
             |:.::...|.::....:             || |.||.|     ||...|        .|..||
  Rat  1139 -SIRISHDKQDKIHTCLE-------------QLFIQLDSITNLLKGRAVVR--------AFEQTK 1181

  Fly   810 LMSSSPSANYYRPTEEPEPLDLTQLNIEASVMCLVSKLKFFCGRCDSPAIRLRHPKAPIKREGFA 874
            .::.......:            |..:||.:.|              |    |..:..:|::
  Rat  1182 YLTPGRGLQEF------------QQEMEAKLSC--------------P----RRLRLHLKQD--- 1213

  Fly   875 VAPQQAPDVIAASAASGKQAPNLALDLKPQSVDSDGITTTGSVAVKKGNKFTDGLDLSMTTDWAA 939
              |...|        ||.:|
  Rat  1214 --PWNLP--------SGVRA--------------------------------------------- 1223

  Fly   940 ELRPSMRKLRHAMDRLLKTARLMHSVQRLQQDMRCNRLQASIMY-------RRDVCFSQALTALV 997
                                 |..|.::..::::|..|.|.:.|       |||:.|.|:|.|.|
  Rat  1224 ---------------------LAQSFRKYVEEVKCRILLALLEYSDSETQLRRDMVFCQSLVATV 1267

  Fly   998 SSLMLRLWGS----------------ELDMGYLVMLRDLGPLAYFEGLLT-LYGNEADMWSDMCI 1045
            .:...:|..:                |....:|..:.:.|.|.:|:.||: ...:|..|..|..:
  Rat  1268 CAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDTLV 1332

  Fly  1046 AIEDLSAVSFQLVRAQGE--VAQTP-TPRITGSRQALEVQL--------PVPEHSLPGNGNSISF 1099
            |:.||..|||....::.|  ||..| |.::.||||||:|..        .:|:....|.|    |
  Rat  1333 ALFDLEKVSFFFKPSEEEPLVANVPLTYQVEGSRQALKVVFYMDSYHFEQLPQRLKNGGG----F 1393

  Fly  1100 KITPVFFNIGIN--EKASFAETLGQTKEQHRSNWDNYLRLSQYFGRYRKLGLGSVDTGESLQSLL 1162
            ||.||.|:..:.  |...:.:.:...:.|.:.|..:..::.||..:.|...|...::..:..|..
  Rat  1394 KIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRAFYLDKSNSPPNATSKA 1458

  Fly  1163 GFMEQQLR------------------------ANV---SKNVKILHLAEDACRLMDGLRFTSCKS 1200
            .::|:.:|                        .|.   :..|.:|.::.:.|..:.......|.|
  Rat  1459 AYIEKLMRPLNALDELYRLVTSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSS 1523

  Fly  1201 AKDRTGMAVTLEQCRVLVREFQLPAKHVPYALSTMRSEGTRMDNVLKNIGKRKYAFNRTQVSFLP 1265
            ...|..::|||||...|.|...||.:::..|...||.:|.|:.|..||:|.|    :||..| .|
  Rat  1524 GVHRCTLSVTLEQAITLARSHGLPPRYIMQATDVMRKQGARVQNTAKNLGVR----DRTPQS-AP 1583

  Fly  1266 AMYR-----PPVG 1273
            .:|:     ||||
  Rat  1584 RLYKLCEPPPPVG 1596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42271	NP_996434.2	PH_INPP4A_INPP4B	1..145	CDD:270091	34/161 (21%)
		PH	21..123	CDD:278594	27/134 (20%)
		C2	201..318	CDD:301316	17/118 (14%)
Prex2	NP_001380724.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910