Protein Alignment CG42271 and PHETA2

DIOPT Version :10

• Sequence 1: NP_996434.2
• Gene: CG42271 / 2768892
• FlyBaseID: FBgn0259166
• Length: 1280
• Species: Drosophila melanogaster
• Sequence 2: NP_001002034.2
• Gene: PHETA2 / 150368
• HGNCID: 27161
• Length: 259
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 55/234 - (23%)
• Similarity: 96/234 - (41%)
• Gaps: 48/234 - (20%)

  Fly    46 WCKLRGNLLFYLKDKDPKSAVAGLLVLENCRARIQNEERDSEGYVFDLDFKDSPSER---FITRS 107
            |..|:|||||..:.::.::.:: |:|||.|...:. |....|.:.|.:.| |:|..|   .....
Human    44 WFVLKGNLLFSFESREGRAPLS-LVVLEGCTVELA-EAPVPEEFAFAICF-DAPGVRPHLLAAEG 105

  Fly   108 SAERLAWVQCIEHASSEKLNALIRQLKEQIVSQSRQP------------SSGASSSMGNHIDLGM 160
            .|.:.|||:.:..||...:..::|:|:.|: ..:||.            :|.......||...|:
Human   106 PAAQEAWVKVLSRASFGYMRLVVRELESQL-QDARQSLALQRRSSWKSVASRCKPQAPNHRAAGL 169

  Fly   161 PLEQQMQEQLQLHGQPAEELSVPV--PTEVVAPFEELDLSELPICETALSCDTLPLDTLGRPPNP 223
            .           :|....:.|.||  ..|..:......|:|..:...|    :|.|.....|.:|
Human   170 E-----------NGHCLSKDSSPVGLVEEAGSRSAGWGLAEWELQGPA----SLLLGKGQSPVSP 219

  Fly   224 QVVC--SLLPTAGEDCV-----WRE-----HARTELQER 250
            :..|  :|....|::.|     |::     |::.|.|:|
Human   220 ETSCFSTLHDWYGQEIVELRQCWQKRAQGSHSKCEEQDR 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42271	NP_996434.2	PH_INPP4A_INPP4B	1..145	CDD:270091	30/113 (27%)
		C2	201..318	CDD:472691	14/62 (23%)
PHETA2	NP_001002034.2	PH-like	11..138	CDD:473070	28/97 (29%)
		F&H	223..235		3/11 (27%)