DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33253 and PHB1

DIOPT Version :9

Sequence 1:NP_001259699.1 Gene:CG33253 / 2768889 FlyBaseID:FBgn0030992 Length:414 Species:Drosophila melanogaster
Sequence 2:NP_011648.3 Gene:PHB1 / 853033 SGDID:S000003364 Length:287 Species:Saccharomyces cerevisiae


Alignment Length:276 Identity:68/276 - (24%)
Similarity:121/276 - (43%) Gaps:50/276 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 ATVVSVLIMVLTFPISVFICFKVVSEYE-----RAVIFRMGRLRSGGAR----GPGVFFVLPCVD 128
            |.::.|:..| ..||.:.......|.|:     |.|||.    |..|.:    |.|..|::|.:.
Yeast     5 AKLIDVITKV-ALPIGIIASGIQYSMYDVKGGSRGVIFD----RINGVKQQVVGEGTHFLVPWLQ 64

  Fly   129 DYYPVDLRTVSFDVPPQEVL----SKDSVTVTVDAVVYYRISDP----LKAVIQVYNYSHSTSLL 185
            .....|:||     .|:.:.    :||...|::...|.:|   |    |.|:.|.....:...:|
Yeast    65 KAIIYDVRT-----KPKSIATNTGTKDLQMVSLTLRVLHR---PEVLQLPAIYQNLGLDYDERVL 121

  Fly   186 AA---TTLRNVLGTRNLSELLTERETISHTMQMSLDEATDPWGVKVERVEIKDVS----LPTALQ 243
            .:   ..|::::...:.:||:|:||.||..::..|....:.:|:|:|.|.|..::    ...|::
Yeast   122 PSIGNEVLKSIVAQFDAAELITQREIISQKIRKELSTRANEFGIKLEDVSITHMTFGPEFTKAVE 186

  Fly   244 RAMAAEAEAAR----------EARAKVIAAEGEMKSSRALREASEIISASPSALQLRYLQTLSSI 298
            :...|:.:|.|          |.:|.||.||||.:|:..:.:|  :.......|.:|.|:....|
Yeast   187 QKQIAQQDAERAKFLVEKAEQERQASVIRAEGEAESAEFISKA--LAKVGDGLLLIRRLEASKDI 249

  Fly   299 S-TEKNSTIIFPLPME 313
            : |..||:.:..||.:
Yeast   250 AQTLANSSNVVYLPSQ 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33253NP_001259699.1 PHB 92..239 CDD:214581 40/170 (24%)
SPFH_SLP-4 112..319 CDD:259813 56/232 (24%)
PHB1NP_011648.3 SPFH_prohibitin 29..223 CDD:259799 51/205 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0330
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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